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Qiagen 凯杰 Biosharp Omega

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Rb X BAL

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货号：AB10618

品牌：Millipore 密理博

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重要规格表

Species Reactivity Key Applications Host Format Antibody Type
H IP, WB Rb Purified Polyclonal Antibody
Description
Catalogue Number AB10618
Brand Family Chemicon®
Trade Name
  • Chemicon
Description Anti-BAL Antibody
Alternate Names
  • B-aggressive lymphoma
Background Information BAL (B-aggressive lymphoma) is a novel risk-related gene that is expressed at significantly higher levels in fatal high-risk diffuse large B-cell lymphomas (DLB-CL) than in cured low-risk tumors. The major BAL cDNA encodes a 88 kDa nuclear protein. BAL-overexpressing B-cell lymphoma transfectants have significantly higher rates of migration than vector-only transfectants, indicating that the risk-related BAL gene promotes malignant B-cell migration.
References
Product Information
Format Purified
Presentation This polyclonal antibody is supplied in 400 μL of phosphate buffered saline (pH 7.4) containing 0.1% sodium azide.
Applications
Application Anti-BAL Antibody is an antibody against BAL for use in IP & WB.
Key Applications
  • Immunoprecipitation
  • Western Blotting
Application Notes Western blotting: 1-3 μg/mL
Immunoprecipitation: 7 μg/ reaction
Biological Information
Immunogen Synthetic peptide derived from the C-terminal region of the short isoform of human BAL protein (B-aggressive lymphoma, poly (ADP-ribose) polymerase family member 9, PARP9).
Concentration Please refer to the Certificate of Analysis for the lot-specific concentration.
Host Rabbit
Specificity Recognizes BAL.
Species Reactivity
  • Human
Species Reactivity Note Reactivity has been confirmed in with human Farage non-Hodgkin's B-cell lymphoma and human BC-1 B-lymphocyte lymphoma lysates.
Antibody Type Polyclonal Antibody
Entrez Gene Number
Gene Symbol
  • PARP9
  • DKFZp666B0810
  • DKFZp686M15238
  • PARP-9
  • BAL1
  • BAL
  • FLJ26637
  • Poly
  • FLJ41418
  • MGC:7868
Purification Method ImmunoAffinity Purified
UniProt Number
UniProt Summary SIZE: 854 amino acids; 96343 Da
SUBUNIT: Interacts with BBAP.
SUBCELLULAR LOCATION: Nucleus.
TISSUE SPECIFICITY: Expressed in lymphocyte-rich tissues, spleen, lymph nodes, peripheral blood lymphocytes and colonic mucosa. Also expressed in nonhematopoietic tissues such as heart and skeletal muscle. Isoform 2 is the predominant form.
SIMILARITY: SwissProt: Q8IXQ6 ## Contains 2 Macro domains. & Contains 1 PARP catalytic domain.
MISCELLANEOUS: Overexpressed at significantly higher levels in fatal high-risk diffuse large B-cell lymphomas (DLB-CL) compared to cured low-risk tumors. Overexpression in B-cell lymphoma transfectants may promote malignant B-cell migration.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions Store at -20°C in undiluted aliquots for 1 year from date of shipment.
Packaging Information
Material Size 100 µg
Transport Information
Supplemental Information
Specifications

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