Anti-Cytochrome C, clone EP1326Y, Rabbit Monoclonal - 炼石商城

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Anti-Cytochrome C, clone EP1326Y, Rabbit Monoclonal

市场价：: 0.00

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货号：04-1043

品牌：Millipore 密理博

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重要规格表

Species Reactivity	Key Applications	Host	Format	Antibody Type
H, M, R	WB	M	Affinity Purified	Monoclonal Antibody

Description
Catalogue Number	MAB1800
Replaces	04-1043
Brand Family	Chemicon®
Trade Name	Chemicon
Description	Anti-Cytochrome C Antibody, clone 7H8.2C12

References

Product Information
Format	Affinity Purified
Presentation	Affinity purified immunoglobulin. Liquid in PBS pH 7.2 containing 50% glycerol and 0.09% sodium azide

Applications
Application	This Anti-Cytochrome C Antibody, clone 7H8.2C12 is validated for use in WB for the detection of Cytochrome C.
Key Applications	Western Blotting
Application Notes	Western blot: 1:400 The antibody detects a 12 kDa protein corresponding to the apparent molecular weight of Cytochrome C. Optimal working dilutions must be determined by end user.

Biological Information
Immunogen	Pigeon Cytochrome C
Clone	7H8.2C12
Concentration	Please refer to the Certificate of Analysis for the lot-specific concentration.
Host	Mouse
Specificity	MAB1800 reacts with denatured human, mouse and rat Cytochrome C. The antibody does not bind native Cytochrome C.
Isotype	IgG2b
Species Reactivity	Human Mouse Rat
Antibody Type	Monoclonal Antibody
Entrez Gene Number	NM_018947.4
Entrez Gene Summary	This gene encodes cytochrome c, a component of the electron transport chain in mitochondria. The heme group of cytochrome c accepts electrons from the b-c1 complex and transfers electrons to the cytochrome oxidase complex. Cytochrome c is also involved in initiation of apoptosis. Upon release of cytochrome c to the cytoplasm, the protein binds apoptotic protease activating factor which activates the apoptotic initiator procaspase 9. Many cytochrome c pseudogenes exist, scattered throughout the human genome.
Gene Symbol	CYCS CYC HCS
UniProt Number	P99999
UniProt Summary	FUNCTION: SwissProt: P99999 # Plays a role in apoptosis. Suppression of the anti- apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases. SIZE: 105 amino acids; 11749 Da SUBCELLULAR LOCATION: Mitochondrion matrix. PTM: Binds 1 heme group per subunit. SIMILARITY: SwissProt: P99999 ## Belongs to the cytochrome c family.

Physicochemical Information

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements
Usage Statement	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage and Shipping Information
Storage Conditions	Maintain frozen at -20°C. For storage up to 12 months, aliquot and refreeze at -20°C or -70°C. Avoid repeated freeze/thaw cycles.

Packaging Information
Material Size	100 µg

Transport Information

Supplemental Information

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