[关闭]
您好！欢迎来到炼石商城   请登录  注册    兼职小伙伴  
我的购物车
0
Qiagen 凯杰 Biosharp Omega

首页抗体Millipore 密理博>

图片仅供参考，请以实物为准
收藏

Anti-SLP 76, clone AS55 (mouse monoclonal)

市场价：
0.00
促销价：
¥0.00

货号：05-1426

品牌：Millipore 密理博

配送至：

支付： 账期 货到付款

数量：

EA (预计3-5工作日到货)

亲，想了解价格请QQ咨询客服！

工作时间

周一至周五：9:00-18:00

咨询电话

0771-3293894

在线咨询

客服 郭恒 蔡玉坤 曾宪飞 技术咨询

浏览了该商品的用户最终购买

RNeasy Mini Kit (50) 50次
RNeasy Mini Kit (50) 50次
3720.00
Plasmid Mini Kit I(200) 200次
Plasmid Mini Kit I(200) 200...
576.00
10ul吸头，透明，袋装，可灭菌 1000支/袋，50袋/箱
10ul吸头，透明，袋装，可灭菌...
85.80

浏览了该商品的用户还浏览了

QIAfilter Plasmid Maxi Kit (10) -10
QIAfilter Plasmid Maxi Kit (...
3000.00
QIAamp DNA Blood Midi Kit (20) 20次
QIAamp DNA Blood Midi Kit (2...
2680.00
QIAamp UCP Pathogen Mini Kit (50)
QIAamp UCP Pathogen Mini Kit...
4112.00
Replacement Information
Replacement Information 05-1426 is a recommended replacement for MAB3756

特卖

100% Performance Guaranteed

重要规格表

Species Reactivity Key Applications Host Format Antibody Type
H, M, R WB, IP M Purified Monoclonal Antibody
Description
Catalogue Number 05-1426
Replaces MAB3756
Description Anti-SLP-76 Antibody, clone AS55
Alternate Names
  • 76 kDa tyrosine phosphoprotein 2
  • Human 76 kDa tyrosine phosphoprotein SLP-76 mRNA, complete cds
  • Lymphocyte cytosolic protein 2
  • SH2 domain-containing leukocyte protein of 76 kDa
  • SLP-76 tyrosine phosphoprotein
  • lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
Background Information Detects SLP-76 (SH2 domain containing Leukocyte Protein) of 76 kDa, a hematopoietic cell-specific adapter protein which intereacts with other signaling molecules through amino-terminal phosphotyrosine residues, a central proline-rich region and a carboxyl-terminal Src homology 2 domain (SH2).
References
Product Information
Format Purified
Control
  • RAW264 cell lysate
Presentation Purified mouse monoclonal IgG2a 0.2 mm sterile filtered solution in phosphate buffered saline with 0.1% sodium azide.
Applications
Application Detect SLP-76 using this Anti-SLP-76 Antibody, clone AS55 validated for use in WB & IP.
Key Applications
  • Western Blotting
  • Immunoprecipitation
Application Notes Immunoprecipitation: A previous lot of this antibody was used in IP.
Optimal working dilutions must be determined by end user.
Biological Information
Immunogen Monoclonal antibody from BALB/c-derived hybridoma
Clone AS55
Concentration Please refer to the Certificate of Analysis for the lot-specific concentration.
Host Mouse
Specificity Recognizes human SH2 (Src homology 2) domain-Leukocyte Protein of 76 kDa.
Isotype IgG2a
Species Reactivity
  • Human
  • Mouse
  • Rat
Species Reactivity Note Human and mouse. Expected to react with rat based on sequence homology.
Antibody Type Monoclonal Antibody
Entrez Gene Number
Entrez Gene Summary SLP-76 was originally identified as a substrate of the ZAP-70 protein tyrosine kinase following T cell receptor (TCR) ligation in the leukemic T cell line Jurkat. The SLP-76 locus has been localized to human chromosome 5q33 and the gene structure has been partially characterized in mice. The human and murine cDNAs both encode 533 amino acid proteins that are 72% identical and comprised of three modular domains. The NH2-terminus contains an acidic region that includes a PEST domain and several tyrosine residues which are phosphorylated following TCR ligation. SLP-76 also contains a central proline-rich domain and a COOH-terminal SH2 domain. A number of additional proteins have been identified that associate with SLP-76 both constitutively and inducibly following receptor ligation, supporting the notion that SLP-76 functions as an adaptor or scaffold protein. Studies using SLP-76 deficient T cell lines or mice have provided strong evidence that SLP-76 plays a positive role in promoting T cell development and activation as well as mast cell and platelet function
Gene Symbol
  • LCP2
  • SLP-76
  • SLP76
Purification Method Protein G Purified
UniProt Number
UniProt Summary FUNCTION: SwissProt: Q13094 # Involved in T-cell antigen receptor mediated signaling.
SIZE: 533 amino acids; 60188 Da
SUBUNIT: Interacts with SLA. Interacts with CBLB (By similarity). Interacts with the adapter proteins GRB2 and FYB. Interacts with SHB. Interacts with PRAM1.
SUBCELLULAR LOCATION: Cytoplasm (Probable).
TISSUE SPECIFICITY: Highly expressed in spleen, thymus, and peripheral blood leukocytes. Highly expressed also in T-cell and monocytic cell lines, expressed at lower level in B-cell lines. Not detected in fibroblast or neuroblasatoma cell lines.
DOMAIN:SwissProt: Q13094 The SH2 domain mediates interaction with SHB.
PTM: Phosphorylated after T-cell receptor activation by ZAP-70.
SIMILARITY: Contains 1 SH2 domain.
Molecular Weight Detects SLP-76 (SH2 domain containing Leukocyte Protein) of 76 kDa
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality Assurance Routinely evaluated by Western Blot on RAW 264 lysates.

Western Blot Analysis: 1:500 dilution of this lot detected SLP-76 on 10 μg of RAW 264 lysates.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions Stable at -20°C in undiluted aliquots for up to 1 year from date of receipt. Avoid repeated freeze/thaw cycles.
Handling Recommendations: Upon first thaw, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Packaging Information
Material Size 100 µg
Transport Information
Supplemental Information
Specifications

温馨提示:因厂家更改产品包装、产地或者更换随机附件等没有任何提前通知，且每位咨询者购买情况、提问时间等不同，为此以下回复仅对提问者3天内有效，其他网友仅供参考！若由此给您带来不便请多多谅解，谢谢！

我要咨询

咨询内容：
购物指南 免费注册 批量采购 购物流程 购物保障
配送方式 上门自提 第三方配送 炼石配送
支付方式 货到付款 账期付款
售后服务 售后政策 退款说明 售后流程 免责条款

服务热线

0771-3293894

关于我们|帮助中心|诚聘英才|炼石云实验室|联系我们|友情链接

Copyright 2014-2025 炼石云商网络科技（海南）有限公司版权所有 琼ICP备2023006525号-3