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Anti-phospho GluR4 (S862) (rabbit polyclonal)

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货号：AB2212

品牌：Millipore 密理博

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重要规格表

Species Reactivity Key Applications Host Format Antibody Type
R WB Rb Serum Polyclonal Antibody
Description
Catalogue Number AB2212
Brand Family Chemicon®
Trade Name
  • Chemicon
Description Anti-phospho GluR4 (S862) Antibody
Background Information Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. Alternative splicing of this gene results in transcript variants encoding different isoforms, which may vary in their signal transduction properties. Some haplotypes of this gene show a positive association with schizophrenia. Direct phosphorylation of GluR4-containing receptors may regulate rapid excitatory synaptic transmission. In addition, phosphorylation of GluR4 S862. is both necessary and sufficient to deliver the receptor to the synapse and induce plasticity in early postnatal development.
References
Product Information
Format Serum
Control
  • Rat Brain Cerebellum lysate
Presentation Serum with 0.05% NaN3
Applications
Application Anti-phospho GluR4 (S862) Antibody is an antibody against phospho GluR4 (S862) for use in WB.
Key Applications
  • Western Blotting
Application Notes Western Blot Analysis:
Cat. # AB2212 recognizes pGluR4 (S862) at 1:5,000 in rat brain cerebellum Lysate.
Biological Information
Immunogen Synthetic peptide from rat.
Host Rabbit
Specificity Cat. # AB2212 recognzies phospho GluR4 (S862).
Species Reactivity
  • Rat
Species Reactivity Note Rat. May react with mouse, human, primate and dog based on sequence homology. Reactivity with other species has not been tested.
Antibody Type Polyclonal Antibody
Gene Symbol
  • GRIA4
  • GLURD
  • GluR-4
  • GluR-D
Modifications
  • Phosphorylation
UniProt Number
Molecular Weight ~105 kDa
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality Assurance Routinely tested on rat brain cerebellum lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions Maintain at -20°C in undiluted aliquots for up to 1 year after date of receipt.
Packaging Information
Material Size 50µL
Transport Information
Supplemental Information
Specifications

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