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Anti-SSTR3 (Rb Polyclonal)

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货号：AB9774-200UL

品牌：Millipore 密理博

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重要规格表

Species Reactivity Key Applications Host Format Antibody Type
R WB Rb Affinity Purified Polyclonal Antibody
Description
Catalogue Number AB9774-200UL
Brand Family Chemicon®
Trade Name
  • Chemicon
Description Anti-Somatostatin Receptor Type 3 Antibody
Alternate Names
  • SSTR3
References
Product Information
Format Affinity Purified
Control
  • Included free of charge with the antibody is 40 µg of control antigen (lyophilized powder). The stock solution of the antigen can be made up using 100 µL of sterile deionized water. For negative control, preincubate 1 µg of peptide with 1 µg of antibody for one hour at room temperature. Optimal concentrations must be determined by the end user
Presentation Affinity purified immunoglobulin. Lyophilized from phosphate buffered saline, pH 7.4, containing 1% BSA, and 0.05% sodium azide as a preservative. Reconstitute with 200 μL of sterile deionized water. Centrifuge antibody preparation before use (10,000 xg for 5 min).
Applications
Application Anti-Somatostatin Receptor Type 3 Antibody detects level of Somatostatin Receptor Type 3 & has been published & validated for use in WB.
Key Applications
  • Western Blotting
Application Notes Western blot: 1:200 using ECL on rat brain lysate.
Dilutions should be made using a carrier protein such as BSA (1-3%).
Optimal working dilutions must be determined by the end user.
Biological Information
Immunogen Purified peptide from amino acids 233-246 of rat SSTR3.
Concentration Please refer to the Certificate of Analysis for the lot-specific concentration.
Host Rabbit
Specificity Recognizes Somatostatin Receptor Type 3 (SSTR3).
Species Reactivity
  • Rat
Species Reactivity Note The immunogen sequence is identical in mouse and 11 of 14 amino acids identical in human.
Antibody Type Polyclonal Antibody
Entrez Gene Summary Somatostatin acts at many sites to inhibit the release of many hormones and other secretory proteins. The biological effects of somatostatin are probably mediated by a family of G protein-coupled receptors that are expressed in a tissue-specific manner. SSTR3 is a member of the superfamily of receptors having seven transmembrane segments and is expressed in highest levels in brain and pancreatic islets. SSTR3 is functionally coupled to adenylyl cyclase.
Gene Symbol
  • SS3R
  • SSR3
  • SSR28
  • SSTR3
Purification Method ImmunoAffinity Purified
UniProt Number
UniProt Summary FUNCTION: SwissProt: P32745 # Receptor for somatostatins-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase.
SIZE: 418 amino acids; 45847 Da
SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein (By similarity). Note=Internalized into endoplasmic vesicles upon somatostatin-stimulation (By similarity).
TISSUE SPECIFICITY: Brain, pituitary and pancreas.
PTM: Phosphorylated. Phosphorylation increases upon somatostatin binding (By similarity).
SIMILARITY: SwissProt: P32745 ## Belongs to the G-protein coupled receptor 1 family.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions Maintain lyophilized material at -20°C for up to 12 months after date of receipt. After reconstitution maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.
Packaging Information
Material Size 200 µL
Transport Information
Supplemental Information
Specifications

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