Milli-Mark™ Anti-CD13-FITC clone WM-47 - 炼石商城

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Milli-Mark™ Anti-CD13-FITC clone WM-47

市场价：: 0.00

促销价：: ¥0.00

货号：FCMAB180F

品牌：Millipore 密理博

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北京朝阳

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Replacement Information

特卖

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重要规格表

Species Reactivity	Key Applications	Host	Format	Antibody Type
H	FC	M	FITC	Monoclonal Antibody

Description
Catalogue Number	FCMAB180F
Trade Name	Milli-Mark
Description	Milli-Mark™ Anti-CD13-FITC Antibody, clone WM-47
Alternate Names	Aminopeptidase N (AP-N), hAPN, Alanyl aminopeptidase, Microsomal aminopeptidase, Aminopeptidase M (AP-M), gp150, Myeloid plasma membrane glycoprotein CD13
Background Information	CD13 is a 150 kDa Type II integral membrane protein composed of 967 amino acids (Turni, 2002; Ashmun, 1995; Look, 1989). CD13 is identical in structure to aminopeptidase N, a membrane-bound zinc-binding metalloprotease (Turni, 2002). CD13 is expressed on the surface of committed granulocyte-monocyte progenitors (CFU-GM) and by cells of the granulocyte and monocyte lineages at all stages of differentiation (Turni, 2002; Ashmun, 1995; Look, 1989). The antigen is also expressed on a small proportion of large granular lymphocytes, but not on B or T cells (Ashmun, 1995; Look, 1989). Further, CD13 is expressed on some non-hematopoietic cells including fibroblasts, endothelial cells, epithelial cells from renal proximal tubules and intestinal brush border, bone marrow stromal cells, osteoclasts, and cells lining the bile duct canaliculi (Turni, 2002; Ashmun, 1995; Look, 1989). Anti-CD13, WM-47, was included in the Fourth and Fifth International Workshop and Conference on Leucocyte Differentiation Antigens and studies by a number of laboratories confirmed its reactivity with CD 13 (Ashmun, 1995; Look, 1989).

References

Product Information
Format	FITC
Control	PBMCs
Presentation	Purified Mouse monoclonal IgG1 conjugated to FITC in 0.05M Tris-HCl buffer with 1% BSA, Sodium Azide at 0.097% at pH 7.2.

Applications
Application	Detect CD13 using this Milli-Mark Anti-CD13-FITC Antibody, clone WM-47 validated for use in FC.
Key Applications	Flow Cytometry

Biological Information
Immunogen	Leukaemic cells from a case of chronic myeloid leukaemia (CML).
Clone	WM-47
Concentration	Please refer to the Certificate of Analysis for the lot-specific concentration.
Host	Mouse
Specificity	Antibody recognizes Human CD13 antigen.
Isotype	IgG1κ
Species Reactivity	Human
Antibody Type	Monoclonal Antibody
Entrez Gene Number	NP_001141.2
Purification Method	Protein A Purfied
UniProt Number	P15144
Molecular Weight	150 kDa (Turni, 2002; Ashmun, 1995; Look, 1989)

Physicochemical Information

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements
Quality Assurance	Evaluated by flow cytometry using human PBMCs
Usage Statement	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage and Shipping Information
Storage Conditions	Maintained refrigerated at 2-8°C from date of receipt. Protected from light in undiluted aliquots for 6 months from date of receipt.

Packaging Information
Material Size	100 tests

Transport Information

Supplemental Information

Specifications

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