Milli-Mark™ Anti-CD11B-PE clone 2LPM19c - 炼石商城

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Milli-Mark™ Anti-CD11B-PE clone 2LPM19c

市场价：: 0.00

促销价：: ¥0.00

货号：FCMAB178P

品牌：Millipore 密理博

配送至：

北京朝阳

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数量：

EA (预计3-5工作日到货)

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Replacement Information

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重要规格表

Species Reactivity	Key Applications	Host	Format	Antibody Type
H	FC	M	Phycoerythrin	Monoclonal Antibody

Description
Catalogue Number	FCMAB178P
Trade Name	Milli-Mark
Description	Milli-Mark™ Anti-CD11B-PE Antibody, clone 2LPM19c
Alternate Names	Integrin alpha-M Cell surface glycoprotein MAC-1 subunit alpha CR-3 alpha chain Leukocyte adhesion receptor MO1 Neutrophil adherence receptor CD11 antigen-like family member B
Background Information	CD11b is the 165 kDa α-chain of the Mac-1 complex. The molecule, also called CR3, functions as a cell surface receptor for the C3bi complement fragment. There is evidence that CD11b can bind fibrinogen in addition to C3bi (Wright,1988). Two binding sites have now been reported, one recognizing lipopolysaccharide, and the other protein ligands containing the arg-gly-asp sequence (Wright, 1989). Binding of the coagulation factor X has also been suggested as an additional receptor role of CD11b (Altieri,1988). This protein belings to a family of related heterodimeric proteins designated CD11 in the classification system for human leucocyte differentiation antigens, which shares a common β-chain with a MW of 95 kDa (CD18). Besides the C3bi receptor, this protein family contains two other members, leucocyte function associated-1 (LFA-1, C11a) antigen and p150,95 protein (CD11c) (Sanchez-Madrid,1983).

References

Product Information
Format	Phycoerythrin
Control	PBMCs
Presentation	Purified Mouse monoclonal IgG1 conjugated to PE in 0.05M Tris-HCl buffer with 1% BSA, Sodium Azide at 0.097% at pH 7.2.

Applications
Application	Milli-Mark Anti-CD11B-PE Antibody, clone 2LPM19c detects level of CD11B & has been published & validated for use in FC.
Key Applications	Flow Cytometry

Biological Information
Immunogen	Purified iC3b receptor.
Clone	2LPM19c
Concentration	Please refer to the Certificate of Analysis for the lot-specific concentration.
Host	Mouse
Specificity	Antibody recognizes Human CD11b antigen.
Isotype	IgG1κ
Species Reactivity	Human
Antibody Type	Monoclonal Antibody
Entrez Gene Number	NP_000623.2
Purification Method	Protein A Purfied
UniProt Number	P11215
Molecular Weight	165 kDa (Wright, 1988)

Physicochemical Information

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements
Quality Assurance	Evaluated by flow cytometry using human PBMCs
Usage Statement	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage and Shipping Information
Storage Conditions	Maintained refrigerated at 2-8°C from date of receipt. Protected from light in undiluted aliquots for 6 months from date of receipt.

Packaging Information
Material Size	100 tests

Transport Information

Supplemental Information

Specifications

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