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Ms Anti-Norepinephrine Transporter

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货号：MAB5620

品牌：Millipore 密理博

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重要规格表

Species Reactivity Key Applications Host Format Antibody Type
H, Mk IHC M Ascites Monoclonal Antibody
Description
Catalogue Number MAB5620
Brand Family Chemicon®
Trade Name
  • Chemicon
Description Anti-Norepinephrine Transporter Antibody
Alternate Names
  • NET
References
Product Information
Format Ascites
Presentation Mouse ascites. Liquid. Contains no preservative.
Applications
Application Detect Norepinephrine Transporter using this Anti-Norepinephrine Transporter Antibody validated for use in IH.
Key Applications
  • Immunohistochemistry
Biological Information
Immunogen Synthetic peptide from human norepinephrine Transporter.
Host Mouse
Specificity Norepinephrine Transporter, human and non-human primate.
Isotype IgG
Species Reactivity
  • Human
  • Monkey
Antibody Type Monoclonal Antibody
Entrez Gene Number
Entrez Gene Summary The SLC6A2 gene encodes a norepinephrine (noradrenaline) transporter, which is responsible for reuptake of norepinephrine into presynaptic nerve terminals and is a regulator of norepinephrine homeostasis (Kim et al., 2006 [PubMed 17146058]).[supplied by OMIM]
Gene Symbol
  • SLC6A2
  • NET
  • SLC6A5
  • NAT1
  • NET1
Purification Method Ascites
UniProt Number
UniProt Summary FUNCTION: SwissProt: P23975 # Amine transporter. Terminates the action of noradrenaline by its high affinity sodium-dependent reuptake into presynaptic terminals.
SIZE: 617 amino acids; 69332 Da
SUBUNIT: Interacts with PRKCABP.
SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
DISEASE: SwissProt: P23975 # Defects in SLC6A2 are a cause of orthostatic intolerance (OI) [MIM:604715]. OI is a syndrome characterized by lightheadedness, fatigue, altered mentation and syncope. It is associated with postural tachycardia. Plasma norepinephrine concentration is abnormally high.
SIMILARITY: SwissProt: P23975 ## Belongs to the sodium:neurotransmitter symporter (SNF) family.
MISCELLANEOUS: This protein is the target of psychomotor stimulants such as amphetamines or cocaine.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.
Packaging Information
Material Size 100 µL
Transport Information
Supplemental Information
Specifications

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