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Anti-Akt2/PKBb

市场价：: 0.00

促销价：: ¥0.00

货号：07-372

品牌：Millipore 密理博

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北京朝阳

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EA (预计3-5工作日到货)

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重要规格表

Species Reactivity	Key Applications	Host	Format	Antibody Type
H, M, R	IP, WB	Rb	Purified	Polyclonal Antibody

Description
Catalogue Number	07-372
Brand Family	Upstate
Trade Name	Upstate
Description	Anti-Akt2/PKBβ Antibody

References

Product Information
Format	Purified
Control	L6 cell lysate
Presentation	Protein A Purified immunoglobulin in 30% glycerol, 0.07M Tris-glycine, pH 7.4, 0.105 M NaCl, 0.035% sodium azide as a preservative.

Applications
Application	This Anti-Akt2/PKBβ Antibody is validated for use in IP, WB for the detection of Akt2/PKBβ.
Key Applications	Immunoprecipitation Western Blotting

Biological Information
Immunogen	peptide (C-RYDSLGSLELDQRTH) corresponding to amino acids 455-469 of human Akt2/PKBb
Concentration	Please refer to the Certificate of Analysis for the lot-specific concentration.
Host	Rabbit
Specificity	Recognizes Akt2/PKBb; does not cross-react with Akt1 or Akt3.
Isotype	IgG
Species Reactivity	Human Mouse Rat
Antibody Type	Polyclonal Antibody
Entrez Gene Number	NM_001626
Entrez Gene Summary	This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. The gene was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phophorylating several known proteins.
Gene Symbol	AKT2 RAC-BETA PRKBB PKBBETA RAC-PK-beta
Purification Method	Protein A Purfied
UniProt Number	P31751
UniProt Summary	FUNCTION: SwissProt: P31751 # General protein kinase capable of phosphorylating several known proteins. SIZE: 481 amino acids; 55769 Da TISSUE SPECIFICITY: In all human cell types so far analyzed. DISEASE:SwissProt: P31751 # Alterations of AKT2 may contribute to the pathogenesis of ovarian carcinomas. SIMILARITY: SwissProt: P31751 ## Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. RAC subfamily. & Contains 1 AGC-kinase C-terminal domain. & Contains 1 PH domain. & Contains 1 protein kinase domain.
Molecular Weight	60 kDa

Physicochemical Information

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements
Quality Assurance	routinely evaluated by immunoblot on RIPA lysates from rat L6 skeletal muscle cells
Usage Statement	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage and Shipping Information
Storage Conditions	Maintain for 2 years at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Packaging Information
Material Size	200 µg

Transport Information

Supplemental Information

Specifications

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