Axltide (Axl/Insulin Receptor substrate peptide)

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Axltide (Axl/Insulin Receptor substrate peptide)

市场价：: 0.00

促销价：: ¥0.00

货号：12-516

品牌：Millipore 密理博

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北京朝阳

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EA (预计3-5工作日到货)

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Replacement Information

Description
Catalogue Number	12-516
Brand Family	Upstate
Trade Name	Upstate
Description	Axltide

References

Product Information
Presentation	Lyophilized powder

Applications
Key Applications	Kinase Assay

Biological Information
Entrez Gene Number	NM_001699.3 NM_021913.2
Entrez Gene Summary	The protein encoded by this gene is a member of the receptor tyrosine kinase subfamily. Although it is similar to other receptor tyrosine kinases, this protein represents a unique structure of the extracellular region that juxtaposes IgL and FNIII repeats. It transduces signals from the extracellular matrix into the cytoplasm by binding growth factors like vitamin K-dependent protein growth-arrest-specific gene 6. It is involved in the stimulation of cell proliferation and can also mediate cell aggregation by homophilic binding. Alternatively spliced transcript variants encoding different isoforms have been identified.
Gene Symbol	AXL UFO
Protein Target	Axl
Target Sub-Family	TK
UniProt Number	P30530
UniProt Summary	FUNCTION: SwissProt: P30530 # May function as a signal transducer between specific cell types of mesodermal origin. SIZE: 887 amino acids; 97437 Da SUBUNIT: Heterodimer and heterotetramer with GAS6. SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein. DISEASE:SwissProt: P30530 # Has transforming potential in patients with chronic myeloproliferative disorder or chronic myelocytic leukemia. SIMILARITY: SwissProt: P30530 ## Belongs to the protein kinase superfamily. Tyr protein kinase family. AXL/UFO subfamily. & Contains 2 fibronectin type-III domains. & Contains 2 Ig-like C2-type (immunoglobulin-like) domains. & Contains 1 protein kinase domain.

Physicochemical Information

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements
Quality Assurance	Routinely evaluated by for use as a substrate in protein kinase assay.
Usage Statement	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage and Shipping Information
Storage Conditions	2 years at -20°C

Packaging Information
Material Size	1 mg

Transport Information

Supplemental Information

Specifications

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实验耗材

分子生物学试剂

蛋白与免疫学

生化试剂

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Axltide (Axl/Insulin Receptor substrate peptide)

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