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Anti-Acinus, NT (AcinusL) (rabbit polyclonal)

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货号：07-447

品牌：Millipore 密理博

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Replacement Information

特卖

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重要规格表

Species Reactivity Key Applications Host Format Antibody Type
H ICC Rb AlexaFluor®647 Polyclonal Antibody
Description
Catalogue Number 07-449-AF647
Description Anti-trimethyl Histone H3 (Lys27), Alexa Fluor® 647 Conjugate Antibody
Alternate Names
  • Histone H3.1t
  • H3/t
  • H3t
  • H3/g
Background Information Histone H3 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N-terminal tail, H3 is involved with the structure of the nucleosomes of the 'beads on a string' structure. Histone proteins are highly post-translationally modified, and Histone H3 is the most extensively modified of the five histones. Histone H3 sequence variants and variable modification states are thought to play a role in the dynamic and long term regulation of genes. Di- and tri-methylation of histone H3 are gene silencing marks, while removal of these marks by the demethylase genes Jmjd1a and Jmjd2c leads to gene activation. This product is a conjugated version of Cat. No. 07-449.
References
Product Information
Format AlexaFluor®647
Presentation Purified rabbit conjugate antibody in buffer containing PBS and 15 mg/ml BSA with 0.1% Sodium Azide.
Applications
Application This Anti-trimethyl Histone H3 (Lys27) antibody is validated for use in ICC for the detection of trimethyl Histone H3 (Lys27).
Key Applications
  • Immunocytochemistry
Biological Information
Immunogen Linear peptide corresponding to Histone H3 trimethylated at Lys27.
Concentration 0.5 mg/mL
Host Rabbit
Species Reactivity
  • Human
Species Reactivity Note Human. Predicted to react with Mouse based on 100% sequence homology.
Antibody Type Polyclonal Antibody
Entrez Gene Number
Gene Symbol
  • HIST3H3
  • H3FT
Purification Method Protein A Purfied
UniProt Number
Molecular Weight ~17 kDa observed (Refer to Cat. No. 07-449)
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality Assurance Evaluated by Immunocytochemistry Analysis: in HeLa cells.

Immunocytochemistry Analysis: A 1:100 dilution of this antibody detected trimethyl Histone H3 (Lys27) in HeLa cells.

Alexa Fluor® is a registered trademark of Life Technologies®.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions Stable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size 100 µL
Transport Information
Supplemental Information
Specifications

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