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Anti-Serotonin Transporter (Rabbit Polyclonal)

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货号：AB9726

品牌：Millipore 密理博

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重要规格表

Species Reactivity Key Applications Host Format Antibody Type
M, R IHC, IP, WB Rb Serum Polyclonal Antibody
Description
Catalogue Number AB9726
Brand Family Chemicon®
Trade Name
  • Chemicon
Description Anti-Serotonin Transporter Antibody
References
Product Information
Format Serum
Presentation Liquid
Applications
Application Anti-Serotonin Transporter Antibody is an antibody against Serotonin Transporter for use in IH, IP & WB.
Key Applications
  • Immunohistochemistry
  • Immunoprecipitation
  • Western Blotting
Application Notes Immunohistochemistry on 4% paraformaldehyde fixed tissues.
Biological Information
Immunogen Fusion protein from the N-terminal of rat Serotonin Transporter.
Host Rabbit
Specificity Serotonin Transporter. By Western blot the antibody recognizes a strong band at ~64 kDa in rat brain extract. The antibody is suitable for detection of the serotonin transporter in the CNS, PNS and peripheral organs where the transporter is present.
Species Reactivity
  • Mouse
  • Rat
Antibody Type Polyclonal Antibody
Entrez Gene Number
Entrez Gene Summary This gene encodes an integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. The encoded protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is a target of psychomotor stimulants, such as amphetamines and cocaine, and is a member of the sodium:neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake and may play a role in sudden infant death syndrome, aggressive behavior in Alzheimer disease patients, and depression-susceptibility in people experiencing emotional trauma.
Gene Symbol
  • SLC6A4
  • 5HTT
  • HTT
  • OCD1
  • hSERT
  • 5-HTT
  • SERT
UniProt Number
UniProt Summary FUNCTION: SwissProt: P31645 # Terminates the action of serotonin by its high affinity sodium-dependent reuptake into presynaptic terminals.
SIZE: 630 amino acids; 70325 Da
SUBUNIT: Interacts with TGFB1I1.
SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
SIMILARITY: SwissProt: P31645 ## Belongs to the sodium:neurotransmitter symporter (SNF) family.
MISCELLANEOUS: This protein is the target of psychomotor stimulants such as amphetamines or cocaine.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.
Packaging Information
Material Size 100 µL
Transport Information
Supplemental Information
Specifications

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