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ANTI-BRAF35, CLONE 4.21 200UG

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号:05-641

牌:Millipore 密理博

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Replacement Information

重要规格表

Species Reactivity Key Applications Host Format Antibody Type
H, M WB M Purified Monoclonal Antibody
Description
Catalogue Number 05-641
Brand Family Upstate
Trade Name
  • Upstate
Description Anti-BRAF35 Antibody, clone 4.21
References
Product Information
Format Purified
Presentation 0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30%
Applications
Application Detect BRAF35 with Anti-BRAF35 Antibody, clone 4.21 (Mouse Monoclonal Antibody), that has been shown to work in WB.
Key Applications
  • Western Blotting
Biological Information
Immunogen GST fusion protein corresponding to residues 100-317 of human BRAF35
Clone clone 4.21
Host Mouse
Specificity BRAF35
Isotype IgG
Species Reactivity
  • Human
  • Mouse
Antibody Type Monoclonal Antibody
Entrez Gene Number
Gene Symbol
  • HMG20B
  • SMARCE1r
  • pp8857
  • PP7706
  • BRAF35
  • SOXL
  • FLJ26127
  • SMARCE1R
  • BRAF25
  • HMGX2
Purification Method Protein G Chromatography
UniProt Number
UniProt Summary FUNCTION: SwissProt: Q9P0W2 # Required for correct progression through G2 phase of the cell cycle and entry into mitosis. Required for RCOR1/CoREST mediated repression of neuronal specific gene promoters.
SIZE: 317 amino acids; 35813 Da
SUBUNIT: Component of a BHC histone deacetylase complex that contains HDAC1, HDAC2, HMG20B/BRAF35, AOF2/LSD1, RCOR1/CoREST and PHF21A/BHC80. The BHC complex may also contain ZMYM2, ZNF217, ZMYM3, GSE1 and GTF2I. Interacts with the BRCA2 tumor suppressor protein.
SUBCELLULAR LOCATION: Nucleus. Note=Localized to condensed chromosomes in mitosis in conjunction with BRCA2.
TISSUE SPECIFICITY: Ubiquitously expressed in adult tissues.
SIMILARITY: SwissProt: Q9P0W2 ## Contains 1 HMG box DNA-binding domain.
Molecular Weight 35kDa
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality Assurance routinely evaluated by immunoblot on HeLa , A431, or 3T3 cell lysates
Sales Restrictions Due to license agreement restrictions, this product cannot be purchased for resale.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions 2 years at -20°C
Packaging Information
Material Size 200 µg
Transport Information
Supplemental Information
Specifications

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