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Qiagen 凯杰 Biosharp Omega

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Rb X Neurotrophin 4 (NT4)

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号:AB1781SP

牌:Millipore 密理博

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EA (预计3-5工作日到货)

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Replacement Information

重要规格表

Species Reactivity Key Applications Host Format Antibody Type
H, M, Mk, R ELISA, WB, IHC, FUNC Rb Purified Polyclonal Antibody
Description
Catalogue Number AB1781SP
Replaces AB1455P
Brand Family Chemicon®
Trade Name
  • Chemicon
Description Anti-Neurotrophin 4/5 Antibody
Alternate Names
  • NT4/5
References
Product Information
Format Purified
Presentation Purified immunoglobulin. Lyophilized from PBS, no preservatives. Reconstitute with 500 μL of sterile distilled water (1 mg/mL).
Applications
Application Anti-Neurotrophin 4/5 Antibody is an antibody against Neurotrophin 4/5 for use in ELISA, WB, IH.
Key Applications
  • ELISA
  • Western Blotting
  • Immunohistochemistry
  • Affects Function
Application Notes Immunohistochemistry: 1-2 μg/mL (see suggested protocol).

Immunoblotting: 1-2 μg/mL

ELISA: 1-2 μg/mL

Inhibition of biological activity in vitro: 1-2 μg/mL.
BIOLOGICAL ACTIVITY: Neutralizes NT4, but not other neurotrophins.

In vivo animal studies: use neat

Optimal working dilutions must be determined by end user.
Biological Information
Immunogen Recombinant human Neurotrophin 4 (NT4).
Host Rabbit
Specificity Neurotrophin 4 (NT4). By dot blot, less than 1% cross-reactivity against NGF, BDNF or NT3.
Species Reactivity
  • Human
  • Mouse
  • Monkey
  • Rat
Antibody Type Polyclonal Antibody
Entrez Gene Number
Entrez Gene Summary This gene is a member of a family of neurotrophic factors, neurotrophins, that control survival and differentiation of mammalian neurons. The expression of this gene is ubiquitous and less influenced by environmental signals. While knock-outs of other neurotrophins including nerve growth factor, brain-derived neurotrophic factor, and neurotrophin 3 prove lethal during early postnatal development, NTF5-deficient mice only show minor cellular deficits and develop normally to adulthood.
Gene Symbol
  • NTF5
  • NT5
  • NT-4
  • NTF4
  • Neurotrophin-4
  • NT-5
  • NT-4/5
  • NT4
UniProt Number
UniProt Summary FUNCTION: SwissProt: P34130 # Target-derived survival factor for peripheral sensory sympathetic neurons.
SIZE: 210 amino acids; 22427 Da
SUBCELLULAR LOCATION: Secreted.
TISSUE SPECIFICITY: Highest levels in prostate, lower levels in thymus, placenta, and skeletal muscle. Expressed in embryonic and adult tissues.
SIMILARITY: SwissProt: P34130 ## Belongs to the NGF-beta family.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions Maintain lyophilized material at -20 to -70°C for up to 12 months after date of receipt. After reconstitution maintain at -20 to -70°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.
Packaging Information
Material Size 500 µg
Transport Information
Supplemental Information
Specifications

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