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Anti-Gb

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货号：06-238

品牌：Millipore 密理博

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Replacement Information

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重要规格表

Species Reactivity Key Applications Host Format Antibody Type
H, M IP, WB Rb Serum Polyclonal Antibody
Description
Catalogue Number 06-238
Brand Family Upstate
Trade Name
  • Upstate
Description Anti-Gβ Antibody
References
Product Information
Format Serum
Presentation PBS, pH 7.2
Applications
Application Detect Gβ using this Anti-Gβ Antibody validated for use in IP & WB.
Key Applications
  • Immunoprecipitation
  • Western Blotting
Biological Information
Immunogen Internal sequence of G-protein β subunit (KTREGNVRVSREL) conjugated to octavalent polylysine base
Host Rabbit
Specificity Gβ subunits; recognizes both isoforms
Isotype IgG
Species Reactivity
  • Human
  • Mouse
Antibody Type Polyclonal Antibody
Entrez Gene Number
Entrez Gene Summary Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. This gene contains a trinucleotide (CCG) repeat length polymorphism in its 5' UTR.
Gene Symbol
  • GNB2
  • SG
  • IG
Purification Method Antiserum
UniProt Number
UniProt Summary FUNCTION: SwissProt: P62879 # Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction.
SIZE: 340 amino acids; 37331 Da
SUBUNIT: G proteins are composed of 3 units, alpha, beta and gamma.
SIMILARITY: SwissProt: P62879 ## Belongs to the WD repeat G protein beta family. & Contains 7 WD repeats.
Molecular Weight 35/36kDa
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality Assurance Immunoblot Analysis: A 1:500-1:1000 dilution of this antibody detected the Gβ subunits in 20 μg of a cell lysate prepared from rat brain microsomal preparation (Catalog # 12-144).

Immunoprecipitation/Immunoblot: 10 μl of this antibody immunoprecipitated the Gβ subunit from 500 μg-1mg of a lysate of rat brain microsomal preparation (Catalog # 12-144).
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions 2 years at -20°C
Packaging Information
Material Size 50 µL
Transport Information
Supplemental Information
Specifications

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