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Anti-PTPA, clone 5G3

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货号：05-941

品牌：Millipore 密理博

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重要规格表

Species Reactivity Key Applications Host Format Antibody Type
H, M WB M Culture Supernatant Monoclonal Antibody
Description
Catalogue Number 05-941
Brand Family Upstate
Trade Name
  • Upstate
Description Anti-PTPA Antibody, clone 5G3
References
Product Information
Format Culture Supernatant
Applications
Application Detect PTPA using this Anti-PTPA Antibody, clone 5G3 validated for use in WB.
Key Applications
  • Western Blotting
Biological Information
Immunogen Full length mouse phosphotyrosyl phosphatase activator protein (PTPA)
Clone clone 5G3
Host Mouse
Specificity PTPA
Species Reactivity
  • Human
  • Mouse
Antibody Type Monoclonal Antibody
Entrez Gene Number
Entrez Gene Summary Protein phosphatase 2A is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2A holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B' family. This gene encodes a specific phosphotyrosyl phosphatase activator of the dimeric form of protein phosphatase 2A. Alternative splicing results in multiple transcript variants encoding different isoforms.
Gene Symbol
  • PPP2R4
  • PR53
  • KIAA0044
  • PTPA
  • MGC2184
  • PP2A
UniProt Number
UniProt Summary FUNCTION: SwissProt: Q15257 # Reversibly stimulates the variable phosphotyrosyl phosphatase activity of PP2A core heterodimer in presence of ATP and Mg(2+) (in vitro).
SIZE: 358 amino acids; 40668 Da
SUBUNIT: Associates with PP2A heterodimeric core enzyme, composed of a 36 kDa catalytic subunit (subunit C) and a 65 kDa constant regulatory subunit (PR65 or subunit A).
TISSUE SPECIFICITY: Widely expressed.
SIMILARITY: SwissProt: Q15257 ## Belongs to the PTPA-type PPIase family.
Molecular Weight 38kDa
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality Assurance Routinely evaluated by immunoblot detecting PTPA in RIPA lysates from HeLa cells.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions 2 years at -20°C from date of shipment
Packaging Information
Material Size 100 µL
Transport Information
Supplemental Information
Specifications

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