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Milli-Mark™ Anti-BMP-7-FITC clone 2A10

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货号：FCMAB136F

品牌：Millipore 密理博

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重要规格表

Species Reactivity Key Applications Host Format Antibody Type
M FC M FITC Monoclonal Antibody
Description
Catalogue Number FCMAB136F
Trade Name
  • Milli-Mark
Description Milli-Mark™ Anti-DPPA-2-FITC Antibody, clone 6C1.2
Alternate Names
  • Pluripotent embryonic stem cell-related gene 1 protein
  • Developmental pluripotency associated 2
Background Information DPPA-2 (developmental pluripotency associated-2) is a novel Oct-4-related protein that is localized to the nucleus of mouse fetal germ cells. DPPA-2 has binding sites for both POU and Sox-2 protein domains and is expressed primarily in the developing germ line following gastrulation. These associations suggest that this protein participates in a very strong supportive role in maintaining cell pluripotentiality. In addition to its role as a pluripotency marker, more recent research using cancer cells suggests that DPPA-2 may also act as an embryo-cancer antigen—pointing to the presence of abnormal cell growth and the formation of cancerous cells.
References
Product Information
Format FITC
Control
  • Mouse ESC (CMTI-2)
Presentation Purified mouse monoclonal IgG2a in buffer containing PBS, 15mg/mL BSA with 0.1% sodium azide.
Applications
Application Milli-Mark Anti-DPPA-2-FITC Antibody, clone 6C1.2 detects level of DPPA-2 & has been published & validated for use in FC.
Key Applications
  • Flow Cytometry
Biological Information
Immunogen Full length recombinant mouse DPPA-2 protein
Clone 6C1.2
Host Mouse
Specificity Antibody recognizes DPPA-2 antigen.
Isotype IgG2aκ
Species Reactivity
  • Mouse
Antibody Type Monoclonal Antibody
Entrez Gene Number
Gene Symbol
  • PESCRG1
Purification Method Protein G Purified
UniProt Number
UniProt Summary FUNCTION: May play a role in maintaining cell pluripotentiality.

SUBCELLULAR LOCATION: Nucleus.

TISSUE SPECIFICITY: Expressed in embryonic stem cells. No expression is seen in 5 months embryo, mesenchymal stem cells, embryonic fibrocytes and adult tissues.

SEQUENCE SIMILARITIES: Contains 1 SAP domain.
Molecular Weight 34 kDa Calculated
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality Assurance Evaluated by flow cytometry using Mouse ESC (CMTI-2)
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions Maintain refrigerated at 2-8°C protected from light in undiluted aliquots for up to 6 months from date of receipt.
Packaging Information
Material Size 100 tests
Transport Information
Supplemental Information
Specifications

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