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Anti-p70 S6 Kinase

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货号：06-926

品牌：Millipore 密理博

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重要规格表

Species Reactivity Key Applications Host Format Antibody Type
H, M, R WB Rb Purified Polyclonal Antibody
Description
Catalogue Number 06-926
Brand Family Upstate
Trade Name
  • Upstate
Description Anti-p70 S6 Kinase (S6K) Antibody
Alternate Names
  • RPS6KB1
  • PS6K
  • S6K
  • S6K1
  • STK14A
  • p70(S6K)-alpha
  • p70-S6K
  • p70-alpha
  • ribosomal protein S6 kinase, 70kDa
References
Product Information
Format Purified
Presentation 0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the additional of glycerol to 30%
Applications
Application Anti-p70 S6 Kinase (S6K) Antibody detects level of p70 S6 Kinase (S6K) & has been published & validated for use in WB.
Key Applications
  • Western Blotting
Biological Information
Immunogen peptide (C-FPMISKRPEHLRMNL) corresponding to residues 511-525 of rat S6 kinase
Host Rabbit
Specificity p70 S6 kinase
Isotype IgG
Species Reactivity
  • Human
  • Mouse
  • Rat
Antibody Type Polyclonal Antibody
Entrez Gene Number
Entrez Gene Summary This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates the S6 ribosomal protein and eucaryotic translation initiation factor 4B (eIF4B). Phosphorylation of S6 leads to an increase in protein synthesis and cell proliferation.
Gene Symbol
  • RPS6KB2
  • P70-beta-1
  • p70-S6KB
  • S6K2
  • S6K-beta
  • P70-BETA
  • STK14B
  • p70S6Kb
  • p70-beta
  • P70-beta-2
  • S6K-beta2
  • p70(S6K)-beta
  • KLS
  • SRK
  • P70-beta
Purification Method Protein A chromatography
UniProt Number
UniProt Summary FUNCTION: SwissProt: Q9UBS0 # Phosphorylates specifically ribosomal protein S6.
SIZE: 482 amino acids; 53483 Da
PTM: Phosphorylated upon DNA damage, probably by ATM or ATR.
SIMILARITY: SwissProt: Q9UBS0 ## Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. & Contains 1 AGC-kinase C-terminal domain. & Contains 1 protein kinase domain.
Molecular Weight 64kDa
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality Assurance routinely evaluated by immunoblot on RIPA lysates from mouse 3T3 cells
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions 2 years at -20°C
Packaging Information
Material Size 200 µg
Transport Information
Supplemental Information
Specifications

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