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Anti-Sec61a

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货号：07-204

品牌：Millipore 密理博

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重要规格表

Species Reactivity Key Applications Host Format Antibody Type
Ca, H, R IP, WB Rb Serum Polyclonal Antibody
Description
Catalogue Number 07-204
Brand Family Upstate
Trade Name
  • Upstate
Description Anti-Sec61α Antibody
References
Product Information
Format Serum
Presentation antiserum containing 0.05% sodium azide and 30% glycerol
Applications
Application Detect Sec61α using this Anti-Sec61α Antibody validated for use in IP & WB.
Key Applications
  • Immunoprecipitation
  • Western Blotting
Biological Information
Immunogen peptide conjugated to KLH and to BSA, corresponding to amino acids 463-476 of human Sec61a (C-KEQSEVGSMGALLF)
Host Rabbit
Specificity Sec61α
Isotype IgG
Species Reactivity
  • Canine
  • Human
  • Rat
Antibody Type Polyclonal Antibody
Entrez Gene Number
Entrez Gene Summary The protein encoded by this gene belongs to the SECY/SEC61- alpha family. It appears to play a crucial role in the insertion of secretory and membrane polypeptides into the endoplasmic reticulum. This protein found to be tightly associated with membrane-bound ribosomes, either directly or through adaptor proteins. This gene encodes an alpha subunit of the heteromeric SEC61 complex, which also contains beta and gamma subunits.
Gene Symbol
  • SEC61A1
  • HSEC61
  • SEC61A
  • SEC61
Purification Method Antiserum
UniProt Number
UniProt Summary FUNCTION: SwissProt: P61619 # Plays a crucial role in the insertion of secretory and membrane polypeptides into the ER. Required for assembly of membrane and secretory proteins. Tightly associated with membrane- bound ribosomes, either directly or through adapter proteins.
SIZE: 476 amino acids; 52265 Da
SUBUNIT: Heterotrimeric complex composed of SEC61-alpha, SEC61- beta and SEC61-gamma.
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane; Multi-pass membrane protein.
SIMILARITY: SwissProt: P61619 ## Belongs to the secY/SEC61-alpha family.
Molecular Weight 40kDa
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality Assurance routinely evaluated by immunoblot on a rat brain microsomal preparation
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions 2 years at -20°C
Packaging Information
Material Size 100 µL
Transport Information
Supplemental Information
Specifications

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