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Rb X Neurofascin 155

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号:AB15189

牌:Millipore 密理博

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Replacement Information

重要规格表

Species Reactivity Key Applications Host Format Antibody Type
M WB Rb Affinity Purified Polyclonal Antibody
Description
Catalogue Number AB15189
Brand Family Chemicon®
Trade Name
  • Chemicon
Description Anti-Neurofascin 155 Antibody
References
Product Information
Format Affinity Purified
Presentation Liquid in PBS with 0.1% sodium azide.
Applications
Application Anti-Neurofascin 155 Antibody is an antibody against Neurofascin 155 for use in WB.
Key Applications
  • Western Blotting
Application Notes Western blot: 0.5-1.0 μg/mL on extracts from mouse brain lysate.

Optimal working dilutions must be determined by the end user.
Biological Information
Immunogen Synethetic peptide.
Host Rabbit
Specificity Neurofascin 155. By Western blot the antibody recognizes a band at ~155 kDa in mouse brain lysate. An additional band at ~80 kDa may be seen depending on sample and antibody concentration used.
Species Reactivity
  • Mouse
Antibody Type Polyclonal Antibody
Entrez Gene Number
Entrez Gene Summary Neurofascin is an L1 family immunoglobulin cell adhesion molecule (see L1CAM; MIM 308840) involved in axon subcellular targeting and synapse formation during neural development (Ango et al., 2004 [PubMed 15479642]).[supplied by OMIM]
Gene Symbol
  • NFASC
  • OTTHUMP00000065315
  • DKFZp686P2250
  • FLJ46866
  • OTTHUMP00000065305
  • OTTHUMP00000065322
  • KIAA0756
  • OTTHUMP00000065324
  • OTTHUMP00000065306
  • OTTHUMP00000065307
  • OTTHUMP00000065321
  • NF
  • neurofascin
  • NRCAML
  • OTTHUMP00000065308
  • OTTHUMP00000065313
Purification Method ImmunoAffinity Purified
UniProt Number
UniProt Summary FUNCTION: SwissProt: O94856 # Cell adhesion, ankyrin-binding protein which may be involved in neurite extension, axonal guidance, synaptogenesis, myelination and neuron-glial cell interactions (By similarity).
SIZE: 1347 amino acids; 150027 Da
SUBUNIT: Probable constituent of a neurofascin/NRCAM/ankyrin-G complex. Associates with the sodium channel beta-1 (SCN1B) and beta-3 (SCN3B) subunits. Interacts with GLDN/gliomedin (By similarity).
SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.
SIMILARITY: SwissProt: O94856 ## Belongs to the immunoglobulin superfamily. L1/neurofascin/NgCAM family. & Contains 5 fibronectin type-III domains. & Contains 6 Ig-like C2-type (immunoglobulin-like) domains.
Molecular Weight 155 kDa
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions Maintain at 2-8°C in undiluted aliquots for up to 6 months after date of receipt.
Packaging Information
Material Size 100 µg
Transport Information
Supplemental Information
Specifications

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