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Rb X ARG3.1 (IgG Fraction)

市场价：: 0.00

促销价：: ¥0.00

货号：AB15467P

品牌：Millipore 密理博

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北京朝阳

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EA (预计3-5工作日到货)

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重要规格表

Species Reactivity	Key Applications	Host	Format	Antibody Type
R	IHC	Rb	Purified	Polyclonal Antibody

Description
Catalogue Number	AB15467P
Brand Family	Chemicon®
Trade Name	Chemicon
Description	Anti-ARG3.1 Antibody
Alternate Names	Growth factor ARC Activity regulated cytoskeleton
Background Information	Arc/Arg3.1 is an immediate-early gene whose mRNA is rapidly transcribed and targeted to dendrites of neurons as they engage in information processing and storage. Arc/Arg3.1 is known to be required for durable forms of synaptic plasticity and learning. Arc/Arg3.1 has been shown to be expressed in neuronal cell bodies and dendrites in the brain regions including striatum and cortex hippocampus.

References

Product Information
Format	Purified
Presentation	Lyophilized. Reconstitute with 50 μL of sterile distilled water. Centrifuge to remove any insoluble material. Contains no preservative.

Applications
Application	Anti-ARG3.1 Antibody detects level of ARG3.1 & has been published & validated for use in IH.
Key Applications	Immunohistochemistry
Application Notes	Immunohistochemistry: 1:200-1:1,000 Optimal working dilutions must be determined by end user.

Biological Information
Immunogen	Synthetic peptide corresponding to a region within the C-terminus of human ARG3.1 protein.
Host	Rabbit
Specificity	ARG3.1 [Growth factor ARC, Activity regulated cytoskeleton]
Species Reactivity	Rat
Antibody Type	Polyclonal Antibody
Entrez Gene Number	NM_015193.3
Gene Symbol	ARC KIAA0278 Arg3.1 NOP NOL3 ARC/ARG3.1 MYC
UniProt Number	Q7LC44
UniProt Summary	FUNCTION: SwissProt: Q7LC44 # Required for consolidation of synaptic plasticity as well as formation of long-term memory. Regulates endocytosis of AMPA receptors in response to synaptic activity. Required for homeostatic synaptic scaling of AMPA receptors (By similarity). SIZE: 396 amino acids; 45316 Da SUBUNIT: Interacts with SH3GL1/endophilin-2, SH3GL3/endophilin-3 and DNM2/DYN2 (By similarity). SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton (By similarity). Endosome (By similarity). Acrosome (By similarity). Cell junction, synapse, postsynaptic cell membrane, postsynaptic density (By similarity). Cell projection, dendrite (By similarity). Cell projection, dendritic spine (By similarity). Cell junction, synapse (By similarity). Note=Associated with the cell cortex of neuronal soma and dendrites. Enriched in postsynaptic density of dendritic spines. Associated with the sperm tail (By similarity). SIMILARITY: SwissProt: Q7LC44 ## Belongs to the ARC/ARG3.1 family.

Physicochemical Information

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements
Usage Statement	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage and Shipping Information
Storage Conditions	Maintain lyophilized material frozen at -20°C to -70°C for up to 12 months after date of receipt. After reconstitution maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles. Glycerol (1:1, ACS or better grade) can be added for additional stability.

Packaging Information
Material Size	500 µg

Transport Information

Supplemental Information

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