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Ms X Hu SP-A

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货号：MAB3280

品牌：Millipore 密理博

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重要规格表

Species Reactivity Key Applications Host Format Antibody Type
H ELISA M Ascites Monoclonal Antibody
Description
Catalogue Number MAB3280
Brand Family Chemicon®
Trade Name
  • Chemicon
Description Anti-Surfactant Protein A Antibody, clone #10
Alternate Names
  • SP-A
References
Product Information
Format Ascites
Presentation Liquid. Contains no preservative
Applications
Application Anti-Surfactant Protein A Antibody, clone #10 is an antibody against Surfactant Protein A for use in ELISA.
Key Applications
  • ELISA
Application Notes Western Blot

ELISA

Optimal dilutions must be determined by the end user.
Biological Information
Immunogen Human SP-A purified from lavage material.
Clone #10
Host Mouse
Specificity Reacts with human SP-A.
Isotype IgG3
Species Reactivity
  • Human
Antibody Type Monoclonal Antibody
Entrez Gene Number
Gene Symbol
  • SFTPA1
  • SFTP1
  • COLEC4
  • PSPA
  • SFTPA
  • PSP-A
  • PSAP
  • SP-A1
  • SP-A
UniProt Number
UniProt Summary FUNCTION: SwissProt: Q8IWL2 # In presence of calcium ions, it binds to surfactant phospholipids and contributes to lower the surface tension at the air-liquid interface in the alveoli of the mammalian lung and is essential for normal respiration.
SIZE: 248 amino acids; 26242 Da
SUBUNIT: Oligomeric complex of 6 set of homotrimers.
SUBCELLULAR LOCATION: Secreted, extracellular space.
DISEASE: SwissProt: Q8IWL2 # Genetic variations in SFTPA1 are associated with respiratory distress syndrome in premature infants (RDS) [MIM:267450]; also known as RDS in prematurity. RDS in the newborn is the main cause of mortality and morbidity in premature infants. RDS is characterized by deficient gas exchange that is caused by diffuse atelectasis and high-permeability lung edema that results in fibrin-rich alveolar deposits called 'hyaline membranes'. The risk of bronchopulmonary dysplasia increases with the severity of RDS.
SIMILARITY: SwissProt: Q8IWL2 ## Contains 1 C-type lectin domain. & Contains 1 collagen-like domain.
MISCELLANEOUS: Pulmonary surfactant consists of 90% lipid and 10% protein. There are 4 surfactant-associated proteins: 2 collagenous, carbohydrate-binding glycoproteins (SP-A and SP-D) and 2 small hydrophobic proteins (SP-B and SP-C).
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions Maintain at -20°C in undiluted aliquots for up to twelve months. Avoid repeated freeze/thaw cycles.
Packaging Information
Material Size 100 µL
Transport Information
Supplemental Information
Specifications

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