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Anti-Tissue Factor, Clone GMA-320, Mouse Monoclonal

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货号：05-881

品牌：Millipore 密理博

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重要规格表

Species Reactivity Key Applications Host Format Antibody Type
H ELISA, WB M Purified Monoclonal Antibody
Description
Catalogue Number 05-881
Brand Family Upstate
Trade Name
  • Upstate
Description Anti-Tissue Factor Antibody, clone GMA-320
References
Product Information
Format Purified
Applications
Application Anti-Tissue Factor Antibody, clone GMA-320 detects level of Tissue Factor & has been published & validated for use in ELISA & WB.
Key Applications
  • ELISA
  • Western Blotting
Biological Information
Immunogen Purified human tissue factor
Clone GMA-320
Host Mouse
Specificity tissue factor
Isotype IgG2a
Species Reactivity
  • Human
Antibody Type Monoclonal Antibody
Entrez Gene Number
Entrez Gene Summary This gene encodes coagulation factor III which is a cell surface glycoprotein. This factor enables cells to initiate the blood coagulation cascades, and it functions as the high-affinity receptor for the coagulation factor VII. The resulting complex provides a catalytic event that is responsible for initiation of the coagulation protease cascades by specific limited proteolysis. Unlike the other cofactors of these protease cascades, which circulate as nonfunctional precursors, this factor is a potent initiator that is fully functional when expressed on cell surfaces. There are 3 distinct domains of this factor: extracellular, transmembrane, and cytoplasmic. This protein is the only one in the coagulation pathway for which a congenital deficiency has not been described.
Gene Symbol
  • F3
  • TF
  • Thromboplastin
  • TFA
  • CD142
Purification Method DEAE purified
UniProt Number
UniProt Summary FUNCTION: SwissProt: P13726 # Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited protolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade.
SIZE: 295 amino acids; 33068 Da
SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.
SIMILARITY: SwissProt: P13726 ## Belongs to the tissue factor family.
Molecular Weight Mr 33kDa
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality Assurance routinely evaluated by immunoblot on human tissue factor
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions stable 2 years at -20°C from date of shipment
Packaging Information
Material Size 100 µg
Transport Information
Supplemental Information
Specifications

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