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Rb X CB2

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货号：AB5642P

品牌：Millipore 密理博

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重要规格表

Species Reactivity Key Applications Host Format Antibody Type
R ELISA, WB Rb Affinity Purified Polyclonal Antibody
Description
Catalogue Number AB5642P
Brand Family Chemicon®
Trade Name
  • Chemicon
Description Anti-Cannabinoid Receptor 2 Antibody, CT
Alternate Names
  • CB2
References
Product Information
Format Affinity Purified
Presentation Affinity purified immunoglobulin. Liquid in phosphate buffered saline, pH 7.4, containing 0.1% BSA.
Applications
Application Detect Cannabinoid Receptor 2 using this Anti-Cannabinoid Receptor 2 Antibody, C-terminus validated for use in ELISA & WB.
Key Applications
  • ELISA
  • Western Blotting
Application Notes Western blot: 1-10 μg/mL using ECL.

ELISA: 1:10,000-1:100,000 using 50-100 ng control peptide (Catalog Number AG214) per well.

Optimal working dilutions must be determined by the end user.
Biological Information
Immunogen An 18 amino acid peptide sequence near the cytoplasmic, C-terminus of rat CB2 (Munro et al. 1993; Shire et al. 1996; Griffin et al. 2000).
Epitope C-terminus
Concentration Please refer to the Certificate of Analysis for the lot-specific concentration.
Host Rabbit
Specificity Recognizes rat Cannabinoid Receptor 2 (CB2). The immunogen shows no significant sequence homology with CB1.

SPECIES REACTIVITIES: The immunogen peptide is 88% conserved in mouse and 82% in human. Reactivity with other species has not been confirmed.
Species Reactivity
  • Rat
Antibody Type Polyclonal Antibody
Entrez Gene Number
Entrez Gene Summary The cannabinoid delta-9-tetrahydrocannabinol is the principal psychoactive ingredient of marijuana. The proteins encoded by this gene and the cannabinoid receptor 1 (brain) (CNR1) gene have the characteristics of a guanine nucleotide-binding protein (G-protein)-coupled receptor for cannabinoids. They inhibit adenylate cyclase activity in a dose-dependent, stereoselective, and pertussis toxin-sensitive manner. These proteins have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. The cannabinoid receptors are members of family 1 of the G-protein-coupled receptors.
Gene Symbol
  • CNR2
  • CB-2
  • OTTHUMP00000044841
  • CB2
  • CX5
UniProt Number
UniProt Summary FUNCTION: SwissProt: P34972 # Involved in cannabinoid-induced CNS effects through G- protein mediated inhibition of adenylate cyclase. Could be a receptor for anandamide.
SIZE: 360 amino acids; 39681 Da
SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
TISSUE SPECIFICITY: Not found in brain. Found in spleen.
SIMILARITY: SwissProt: P34972 ## Belongs to the G-protein coupled receptor 1 family.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions Maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.
Packaging Information
Material Size 50 µg
Transport Information
Supplemental Information
Specifications

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