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Chk X MAP2

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货号：AB15452

品牌：Millipore 密理博

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重要规格表

Species Reactivity Key Applications Host Format Antibody Type
M ICC, IHC Ch Affinity Purified Polyclonal Antibody
Description
Catalogue Number AB15452
Brand Family Chemicon®
Trade Name
  • Chemicon
Description Anti-MAP2 Antibody
Alternate Names
  • Microtubule associated protein 2
References
Product Information
Format Affinity Purified
Presentation Affinity purified chicken immunoglobulin. Two different antibodies were combined to make this product. Liquid in PBS, pH 7.2 with 0.02% sodium azide.
Applications
Application Anti-MAP2 Antibody detects level of MAP2 & has been published & validated for use in IC, IH.
Key Applications
  • Immunocytochemistry
  • Immunohistochemistry
Application Notes Immunohistochemistry: 1:1000-1:2,000 using 2% paraformaldehyde fixed tissue.

Immunocytochemistry: 1:1000-1:2,000 using 2% paraformaldehyde fixed cells.

Optimal working dilutions must be determined by end user.
Biological Information
Immunogen Synthetic peptides corresponding to different regions of the human/mouse MAP2 protein.
Host Chicken
Specificity MAP2 [Microtubule associated protein 2]
Species Reactivity
  • Mouse
Species Reactivity Note Other species have not yet been tested. It is expected that the antibody will also react with human due to immunogen sequence similarity.
Antibody Type Polyclonal Antibody
Entrez Gene Number
Entrez Gene Summary This gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are thought to be involved in microtubule assembly, which is an essential step in neurogenesis. The products of similar genes in rat and mouse are neuron-specific cytoskeletal proteins that are enriched in dentrites, implicating a role in determining and stabilizing dentritic shape during neuron development. A number of alternatively spliced variants encoding distinct isforms have been described.
Gene Symbol
  • MAP2
  • MAP2B
  • MAP-2
  • MAP2C
  • DKFZp686I2148
  • MAP2A
Purification Method ImmunoAffinity Purified
UniProt Number
UniProt Summary FUNCTION: SwissProt: P11137 # The exact function of MAP2 is unknown but MAPs may stabilize the microtubules against depolymerization. They also seem to have a stiffening effect on microtubules.
SIZE: 1827 amino acids; 199539 Da
PTM: MAP2A/c is phosphorylated. Phosphorylated upon DNA damage, probably by ATM or ATR.
SIMILARITY: SwissProt: P11137 ## Contains 3 Tau/MAP repeats.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions Maintain at 2-8°C in undiluted aliquots for up to 6 months after date of receipt.
Packaging Information
Material Size 500 µL
Transport Information
Supplemental Information
Specifications

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