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Anti-KDR/Flk-1, clone CH-11

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货号：05-554

品牌：Millipore 密理博

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重要规格表

Species Reactivity Key Applications Host Format Antibody Type
H, M ELISA, ICC, WB M Purified Monoclonal Antibody
Description
Catalogue Number 05-554
Brand Family Upstate
Trade Name
  • Upstate
Description Anti-KDR/Flk-1/VEGFR2 Antibody, clone CH-11
References
Product Information
Format Purified
Presentation 20mM sodium phosphate, pH 7.6, 250mM NaCl with 0.1% sodium azide
Applications
Application Anti-KDR/Flk-1/VEGFR2 Antibody, clone CH-11 detects level of KDR/Flk-1/VEGFR2 & has been published & validated for use in ELISA, IC & WB.
Key Applications
  • ELISA
  • Immunocytochemistry
  • Western Blotting
Biological Information
Immunogen Recombinant protein corresponding to residues 1158-1345 of murine KDR/Flk-1
Clone clone CH-11
Host Mouse
Specificity KDR/Flk-1
Isotype IgG1
Species Reactivity
  • Human
  • Mouse
Antibody Type Monoclonal Antibody
Entrez Gene Number
Gene Symbol
  • KDR
  • VEGFR-2
  • VEGFR2
  • VEGFR
  • CD309
  • FLK1
Purification Method Protein A chromatography
UniProt Number
UniProt Summary FUNCTION: SwissProt: P35968 # Receptor for VEGF or VEGFC. Has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.
SIZE: 1356 amino acids; 151527 Da
SUBUNIT: Interacts with SHB upon VEGF activation. Interacts with HIV-1 Tat.
SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.
SIMILARITY: SwissProt: P35968 ## Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. & Contains 7 Ig-like C2-type (immunoglobulin-like) domains. & Contains 1 protein kinase domain.
Molecular Weight 230kDa
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality Assurance routinely evaluated by immunoblot on RIPA lysates from HUVEC cells
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions 2 years at 4°C
Packaging Information
Material Size 100 µg
Transport Information
Supplemental Information
Specifications

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