[关闭]
您好!欢迎来到炼石商城   请登录  注册    兼职小伙伴  
我的购物车
0
Qiagen 凯杰 Biosharp Omega

首页抗体Millipore 密理博>

图片仅供参考,请以实物为准
收藏

Anti-Aldehyde dehydrogenase 1 (ALDH1A1) (rabbit polyclonal)

价:
0.00
价:
¥0.00

号:ABD12

牌:Millipore 密理博

账期 货到付款

EA (预计3-5工作日到货)

亲,想了解价格请QQ咨询客服!

工作时间

周一至周五:9:00-18:00

咨询电话

0771-3293894

在线咨询

客服 郭恒 蔡玉坤 曾宪飞 技术咨询

浏览了该商品的用户还浏览了

Replacement Information

重要规格表

Species Reactivity Key Applications Host Format Antibody Type
H WB Rb Affinity Purified Polyclonal Antibody
Description
Catalogue Number ABD12
Description Anti-Aldehyde dehydrogenase 1 (ALDH1A1) Antibody
Alternate Names
  • aldehyde dehydrogenase 1 family, member A1
  • ALDH class 1
  • Aldehyde dehydrogenase, cytosolic
  • retinaldehyde dehydrogenase 1
  • Aldehyde dehydrogenase family 1 member A1
  • retinal dehydrogenase 1
  • acetaldehyde dehydrogenase 1
  • aldehyde dehydrogenase 1, soluble
  • aldehyde dehydrogenase, liver cytosolic
Background Information Aldehyde dehydrogenase 1A1 (ALDH1A1) is also known as retinal dehydrogenase 1. It is thought to be a main converter of retinol to retinoic acid, which is very important in cell to cell signaling. ALDH1A1 may also be involved in inhibiting invasion in pancreatic cancer cells. More specifically, ALDH1A1 may regulate hematopoietic stem cell differentiation by disrupting the retinoid signaling.
References
Product Information
Format Affinity Purified
Control
  • HepG2 cell lysate
Presentation Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Applications
Application This Anti-Aldehyde dehydrogenase 1 (ALDH1A1) Antibody is validated for use in WB for the detection of Aldehyde dehydrogenase 1 (ALDH1A1).
Key Applications
  • Western Blotting
Biological Information
Immunogen KLH-conjugated linear peptide corresponding to human Aldehyde dehydrogenase 1.
Concentration Please refer to the Certificate of Analysis for the lot-specific concentration.
Host Rabbit
Species Reactivity
  • Human
Species Reactivity Note Demonstrated to react with human.
Other homologies: rat and mouse (91% sequence homology).
Antibody Type Polyclonal Antibody
Entrez Gene Number
Entrez Gene Summary This protein belongs to the aldehyde dehydrogenases family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of this enzyme, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of Orientals have only the cytosolic isozyme, missing the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of the mitochondrial isozyme. This gene encodes a cytosolic isoform, which has a high affinity for aldehydes. [provided by RefSeq].
Gene Symbol
  • RALDH1
  • ALDH11
  • ALHDII
  • ALDC
  • ALDH-E1
  • ALDH1
  • PUMB1
  • RalDH1
  • RALDH 1
  • ALDH1A1
Purification Method Affinity Purfied
UniProt Number
UniProt Summary FUNCTION: Binds free retinal and cellular retinol-binding protein-bound retinal. Can convert/oxidize retinaldehyde to retinoic acid (By similarity).

CATALYTIC ACTIVITY: Retinal + NAD+ + H2O = retinoate + NADH.

PATHWAY: Cofactor metabolism; retinol metabolism.

SUBUNIT STRUCTURE: Homotetramer.

SUBCELLULAR LOCATION: Cytoplasm.

SEQUENCE SIMILARITIES: Belongs to the aldehyde dehydrogenase family.
Molecular Weight ~54 kDa observed
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality Assurance Evaluated by Western Blot in HepG2 cell lysate.

Western Blot Analysis: 0.05 µg/mL of this antibody detected Aldehyde dehydrogenase 1 on 10 µg of HepG2 cell lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions Stable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size 100 µg
Transport Information
Supplemental Information
Specifications

温馨提示:因厂家更改产品包装、产地或者更换随机附件等没有任何提前通知,且每位咨询者购买情况、提问时间等不同,为此以下回复仅对提问者3天内有效,其他网友仅供参考!若由此给您带来不便请多多谅解,谢谢!

我要咨询

咨询内容:
支付方式 货到付款 账期付款

服务热线

0771-3293894