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Anti-Galanin (rabbit polyclonal)

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货号：AB2233

品牌：Millipore 密理博

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重要规格表

Species Reactivity Key Applications Host Format Antibody Type
R IH(P) Rb Serum Polyclonal Antibody
Description
Catalogue Number AB2233
Description Anti-Galanin Antibody
Alternate Names
  • galanin prepropeptide
  • galanin-message-associated peptide
  • galanin-related peptide
Background Information Galanin is a neuropeptide which is not a member of any known family of neuropeptides, despite repeated efforts to discover related peptides. Its actions are mediated via Gi-protein-coupled receptors (GPCR’s) and ion channels, usually producing inhibition of secretion of a transmitter or hormone in the nervous and endocrine system. In many respects, these inhibitory actions of galanin remind us of those of gamma-aminobutyric acid (GABA) and of neuropeptide Y (NPY). Galanin coexists with GABA, noradrenaline, 5-hydroxytryptamine (5-HT), and NPY in several regions of the brain. Galanin and it’s receptor are over expressed in limbic region of the brain in patients suffering from Alzheimer's disease. However it is not clear whether galanin exacerbates or is a protective response to the disease.
References
Product Information
Format Serum
Control
  • Rat Cerebellum Tissue
Presentation Serum with 0.05% NaN3
Applications
Application Detect Galanin using this Anti-Galanin Antibody validated for use in IH(P).
Key Applications
  • Immunohistochemistry (Paraffin)
Biological Information
Immunogen Synthetic Linear Peptide
Host Rabbit
Specificity Cat. # AB2233 recognizes Galanin
Species Reactivity
  • Rat
Species Reactivity Note Rat. May react with mouse, human and Sus Scrofa based on sequence homology. Reactivity with other species has not been determined.
Antibody Type Polyclonal Antibody
Entrez Gene Number
Gene Symbol
  • GAL1
  • GALN
  • GLNN
  • GMAP
  • MGC40167
  • galanin
UniProt Number
UniProt Summary FUNCTION: Contracts smooth muscle of the gastrointestinal and genitourinary tract, regulates growth hormone release, modulates insulin release, and may be involved in the control of adrenal secretion.
LOCATION: Secreted.
SIMILARITY: Belongs to the galanin family.
Molecular Weight 13.3 kDa
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality Assurance Routinely evaluated by Immunhistochemistry on rat cerebellum tissue.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions Maintain at -20°C for up to 1 year from date of receipt.
Packaging Information
Material Size 100 µL
Transport Information
Supplemental Information
Specifications

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