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Anti-Notch 1, clone 8G10

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号:05-557

牌:Millipore 密理博

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Replacement Information

重要规格表

Species Reactivity Key Applications Host Format Antibody Type
M, R FC, ICC, WB SHm Culture Supernatant Monoclonal Antibody
Description
Catalogue Number 05-557
Brand Family Upstate
Trade Name
  • Upstate
Description Anti-Notch 1 Antibody, clone 8G10
Background Information The notch gene belongs to a family of epidermal growth factor (EGF) like homeotic genes, which encode transmembrane proteins with a variable number of cysteine-rich EGF-like repeats in the extracellular region. Four notch genes have been described in mammals, which include notch-1. notch-2, notch-3, and notch-4(Int-3), which have been implicated in the differentiation of the nervous system and other structures. The EGF-like proteins Delta and Serrate have been identified as ligands of notch-1. Mature notch proteins are heterodimeric receptors derived from the cleavage of notch pre-proteins into an extracellular subunit (NEC) containing multiple EGF-like repeats and a transmembrane subunit including intracellular region (Ntm).
References
Product Information
Format Culture Supernatant
Control
  • C2C12 cell lysate, breast, colon carcinoma
Presentation Cell Culture supernatant
Applications
Application Detect Notch 1 with Anti-Notch 1 Antibody, clone 8G10 (Syrian Hamster Monoclonal Antibody), that has been shown to work in FC, ICC & WB.
Key Applications
  • Flow Cytometry
  • Immunocytochemistry
  • Western Blotting
Biological Information
Immunogen Residues 1299-1492 of murine notch 1
Clone 8G10
Concentration Please refer to the Certificate of Analysis for the lot-specific concentration.
Host Syrian Hamster
Specificity Recognizes Notch 1.
Isotype IgG
Species Reactivity
  • Mouse
  • Rat
Antibody Type Monoclonal Antibody
Entrez Gene Number
Gene Symbol
  • NOTCH1
Purification Method Unpurified
UniProt Number
Molecular Weight 300 kDa
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality Assurance routinely evaluated by immunoblot on mouse C2C12 muscle myoblast cells
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions Maintain for 2 years at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Packaging Information
Material Size 200 µL
Transport Information
Supplemental Information
Specifications

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