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Anti-EAPP, clone 1E4

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货号：04-086

品牌：Millipore 密理博

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重要规格表

Species Reactivity Key Applications Host Format Antibody Type
H WB M Ascites Monoclonal Antibody
Description
Catalogue Number 04-086
Brand Family Upstate
Trade Name
  • Upstate
Description Anti-EAPP Antibody
Alternate Names
  • E2F-associated phosphoprotein
Background Information E2F transcription factors regulate cell cycle progression and cell proliferation by controlling the expression of genes required for G1/S transition. E2F also up-regulates expression of genes involved in DNA replication and repair. E2F activity is frequently deregulated in human cancers, and may be involved in
tumorigenesis. EAPP (e2F-associated phosphoprotein) is an E2F- binding protein that modulates E2F activity in a cell cycledependent
manner. EAPP is localized in the nucleus and interacts with E2F-1, E2F-2, and E2F-3, but not with E2F-4. Overexpression of EAPP resulted in an increase of cells in Sphase, implying a role for EAPP in stimulating E2F-regulated proliferation.
References
Product Information
Format Ascites
Presentation Mouse ascites containing 0.05% sodium azide
Applications
Application Use Anti-EAPP Antibody (Mouse Monoclonal Antibody) validated in WB to detect EAPP also known as E2F-associated phosphoprotein.
Key Applications
  • Western Blotting
Biological Information
Immunogen GST fusion protein corresponding to the N terminus of human E2F-associated phosphoprotein (EAPP)
Epitope N-terminus
Clone 1E4
Host Mouse
Specificity Human EAPP
Isotype IgG
Species Reactivity
  • Human
Antibody Type Monoclonal Antibody
Gene Symbol
  • EAPP
Purification Method Mouse ascites
UniProt Number
Molecular Weight 42 kDa
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality Assurance This antibody is routinely evaluted in lysates from HEK293 cells, probed with Anti-EAPP, clone 1E4 (1:1000).
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt
Packaging Information
Material Size 100 µL
Transport Information
Supplemental Information
Specifications

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