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Qiagen 凯杰 Biosharp Omega

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Rb X Mouse Per 3

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0.00
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¥0.00

货号：AB5430P

品牌：Millipore 密理博

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重要规格表

Species Reactivity Key Applications Host Format Antibody Type
M ELISA, WB Rb Affinity Purified Polyclonal Antibody
Description
Catalogue Number AB5430P
Brand Family Chemicon®
Trade Name
  • Chemicon
Description Anti-Per3 Antibody
Alternate Names
  • Period Circadian Protein 3
References
Product Information
Format Affinity Purified
Presentation Affinity purified immunoglobulin. Liquid in PBS, containing 0.1% BSA .
Applications
Application Anti-Per3 Antibody is an antibody against Per3 for use in ELISA & WB.
Key Applications
  • ELISA
  • Western Blotting
Application Notes Western blot: 1-10 μg/mL using ECL.

ELISA: 1:10,000-1:100,000 using 50-100 ng control peptide per well.

Optimal working dilutions must be determined by the end user.
Biological Information
Immunogen A 20 amino acid peptide sequence within the C-teriminus of mouse Per 3 (Zylka, 1998).
Concentration Please refer to the Certificate of Analysis for the lot-specific concentration.
Host Rabbit
Specificity Recognizes mouse Per 3. . Reactivity with other species has not been confirmed. The immunogen sequence shows 77% homology with mouse Per3 and 50% with human and drosophila.
Species Reactivity
  • Mouse
Antibody Type Polyclonal Antibody
Entrez Gene Number
Entrez Gene Summary This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. Circadian expression in the suprachiasmatic nucleus continues in constant darkness, and a shift in the light/dark cycle evokes a proportional shift of gene expression in the suprachiasmatic nucleus. The specific function of this gene is not yet known.
Gene Symbol
  • PER3
  • hPER3
  • GIG13
  • ORFNames=GIG13
UniProt Number
UniProt Summary FUNCTION: SwissProt: P56645 # Component of the circadian clock mechanism which is essential for generating circadian rhythms. Function unknown.
SIZE: 1201 amino acids; 131872 Da
SUBUNIT: Homodimer. Component of the circadian core oscillator, which includes the CRY proteins, CLOCK or NPAS2, BMAL1 or BMAL2, CSNK1D and/or CSNK1E, TIMELESS and the PER proteins. Interacts directly with PER1, PER2, CRY1, CRY2, and TIMELESS. Interaction with CSNK1D or CSKN1E promotes nuclear location of PER proteins (By similarity).
SUBCELLULAR LOCATION: Cytoplasm (By similarity). Nucleus (By similarity). Note=Mainly cytoplasmic. Translocates to the nucleus through binding PER1, PER2, CRY1 or CRY2, but not TIMELESS (By similarity).
PTM: Phosphorylation appears to require association with PER1 and translocation to the nucleus (By similarity). & Ubiquitinated (By similarity).
SIMILARITY: SwissProt: P56645 ## Contains 1 PAC (PAS-associated C-terminal) domain. & Contains 2 PAS (PER-ARNT-SIM) domains.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions Maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.
Packaging Information
Material Size 50 µg
Transport Information
Supplemental Information
Specifications

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