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GPCR G2A, RBX-25UG

市场价：: 0.00

促销价：: ¥0.00

货号：AB9860

品牌：Millipore 密理博

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北京朝阳

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EA (预计3-5工作日到货)

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重要规格表

Species Reactivity	Key Applications	Host	Format	Antibody Type
R	IH(P)	Rb	Affinity Purified	Polyclonal Antibody

Description
Catalogue Number	AB9860
Brand Family	Chemicon®
Trade Name	Chemicon
Description	Anti-GPCR G2A Antibody
Alternate Names	G protein-coupled receptor G2A

References

Product Information
Format	Affinity Purified
Presentation	Affinity purified immunoglobulin. Liquid in 0.1M Glycine / 0.2M Tris buffer solution pH7.8 containing 0.02% sodium azide.

Applications
Application	Anti-GPCR G2A Antibody detects level of GPCR G2A & has been published & validated for use in IH(P).
Key Applications	Immunohistochemistry (Paraffin)
Application Notes	Immunohistochemistry on formalin fixed, paraffin embedded rat urinary tissue. Optimal working dilutions must be determined by the end user.

Biological Information
Immunogen	Highly purified peptide from C-terminus of rat G2A.
Concentration	Please refer to the Certificate of Analysis for the lot-specific concentration.
Host	Rabbit
Specificity	Recognizes rat GPCR G2A (G protein-coupled receptor G2A
Species Reactivity	Rat
Antibody Type	Polyclonal Antibody
Entrez Gene Number	NM_013345.2
Entrez Gene Summary	This gene encodes a subfamily member of the G-protein couple receptor (GPCR) superfamily. The encoded protein is a high-affinity receptor for lysophosphatidylcholine (LPC), a major phospholipid component of oxidized low density lipoprotein. This protein may react to LPC levels at sites of inflammation to limit the expansion of tissue-infiltrating cells. A similar protein in mouse is involved in cell cycle progression.
Gene Symbol	GPR132 G2A MGC99642
Purification Method	ImmunoAffinity Purified
UniProt Number	Q9UNW8
UniProt Summary	FUNCTION: SwissProt: Q9UNW8 # Receptor for an unknown ligand. Activates a G alpha protein, most likely G alpha(q). May be involved in apoptosis. Functions at the G2/M checkpoint to delay mitosis. May serve as a mechanism for T- and B-cells, and other cell types, to slow their proliferation and repair damaged DNA to ensure proper replication. SIZE: 380 amino acids; 42499 Da SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein (Probable). Note=Internalized and accumulated in endosomal compartments. LPC triggers the relocalization from the endosomal compartment to the cell surface (By similarity). TISSUE SPECIFICITY: Highly expressed in macrophages and hematopoietic tissues rich in lymphocytes, like spleen and thymus. Weakly expressed in heart and lung. In atherosclerotic plaques, expression is observed around the lipid core and at the shoulder region. SIMILARITY: SwissProt: Q9UNW8 ## Belongs to the G-protein coupled receptor 1 family.

Physicochemical Information

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements
Usage Statement	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage and Shipping Information
Storage Conditions	Maintain lyophilized material at -20°C for up to 12 months after date of receipt. After reconstitution maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Packaging Information
Material Size	25 µg

Transport Information

Supplemental Information

Specifications

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