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Qiagen 凯杰 Biosharp Omega

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Anti-p47-phox (rabbit antiserum)

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号:07-497

牌:Millipore 密理博

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Replacement Information

重要规格表

Species Reactivity Key Applications Host Format Antibody Type
R IH(P) Rb Serum Polyclonal Antibody
Description
Catalogue Number 07-1497
Replaces MABN1026
Description Anti-cAMP Antibody
Background Information Cyclic adenosine monophosphate or cAMP is an intracellular by-product of ATP by adenylene cyclase when G-protein Coupled Receptors (GPCR) bind various ligands on the cell surface. Cyclic AMP acts as a second messenger for signal transduction across the cell membrane and is a part of kinase activation. It regulates the effects of glucagon and adrenaline along with the movement of calcium ions through ion channels. Since it is affected directly by GPCR activation, cAMP is studied as a means to monitor GPCR in the discovery of therapeutic drugs.
References
Product Information
Format Serum
Control
  • Rat hippocampus and cerebellum tissue
Presentation Diluted serum presented as liquid in PBS containing no preservatives.
Applications
Application Anti-cAMP Antibody detects level of cAMP & has been published & validated for use in IH(P).
Key Applications
  • Immunohistochemistry (Paraffin)
Biological Information
Immunogen 2'O-succinyl cyclic AMP conjugated to BSA
Host Rabbit
Specificity Specific for cAMP with no cross reaction to other nucleotides at concentrations to 1 mM. Reactive with cAMP fixed in tissues or acetylated cAMP. Not reactive with free, non-acetylated, cAMP in RIA or EIA assays.
Species Reactivity
  • Rat
Species Reactivity Note Proven to react with rat. Expected to react with all species.
Antibody Type Polyclonal Antibody
Purification Method Unpurified rabbit serum
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality Assurance Evaluated by Immunohistochemistry in rat hippocampus and cerebellum tissue.
Immunohistochemistry Analysis: 1:100 dilution of this lot detected cAMP in rat hippocampus and cerebellum tissue.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions Maintain at -20°C in undiluted aliquots from date of shipment. Avoid repeated freeze/thaw cycles.
Packaging Information
Material Size 50 µL
Transport Information
Supplemental Information
Specifications

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