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Anti-Brain lipid binding protein (rabbit polyclonal)

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货号：ABN14

品牌：Millipore 密理博

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重要规格表

Species Reactivity Key Applications Host Format Antibody Type
M, H WB, IHC Rb Affinity Purified Polyclonal Antibody
Description
Catalogue Number ABN14
Replaces AB9558
Description Anti-Brain lipid binding protein Antibody
Alternate Names
  • Brain lipid-binding protein
  • Fatty acid-binding protein 7
  • Mammary-derived growth inhibitor related
  • brain lipid binding protein
  • fatty acid binding protein 7, brain
  • mammary-derived growth inhibitor-related
Background Information BLBP (Brain lipid-binding protein) belongs to a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. BLBPs play essential roles in fatty acid uptake, transport and metabolism. BLBP can be used as a molecular marker for radial glia (a major neural progenitor cell type and a scaffolding supporting neuronal migration) in the developing central nervous system. Radial glia play an essential role in the generation of the cerebral cortex through their function as neuronal precursors and as neuronal migration guides.
References
Product Information
Format Affinity Purified
Control
  • P1 mouse brain tissue lysate
Presentation Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.05% sodium azide.
Applications
Application Detect Brain lipid binding protein using this Anti-Brain lipid binding protein Antibody validated for use in WB, IH.
Key Applications
  • Western Blotting
  • Immunohistochemistry
Application Notes Immunohistochemistry Analysis: A 1:300 dilution of ABN14 antibody from a previous lot detected Brain lipid binding protein in mouse cerebellum tissue.
Biological Information
Immunogen GST-tagged recombinant protein corresponding to human Brain lipid-binding protein.
Epitope Cytoplasmic Domain
Concentration Please refer to the Certificate of Analysis for the lot-specific concentration.
Host Rabbit
Specificity This antibody recognizes Brain lipid-binding protein.
Species Reactivity
  • Mouse
  • Human
Species Reactivity Note Proven to react with mouse. Predicted to react with human based on 100% sequence homology. Rat homology - 88%.
Antibody Type Polyclonal Antibody
Entrez Gene Number
Entrez Gene Summary The protein encoded by this gene is a brain fatty acid binding protein. Fatty acid binding proteins (FABPs) are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABPs are thought to play roles in fatty acid uptake, transport, and metabolism. [provided by RefSeq].
Gene Symbol
  • FABP7
  • B-FABP
  • MRG
  • BLBP
  • FABPB
Purification Method Affinity Purfied
UniProt Number
UniProt Summary FUNCTION: B-FABP could be involved in the transport of a so far unknown hydrophobic ligand with potential morphogenic activity during CNS development. It is required for the establishment of the radial glial fiber system in developing brain, a system that is necessary for the migration of immature neurons to establish cortical layers By similarity.

SUBCELLULAR LOCATION: Cytoplasm.

TISSUE SPECIFICITY: Expressed in brain and other neural tissues.

DOMAIN: Forms a beta-barrel structure that accommodates the hydrophobic ligand in its interior.

SEQUENCE SIMILARITIES: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
Molecular Weight ~ 15 kDa
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality Assurance Evaluated by Western Blot in P1 mouse brain tissue lysate.

Western Blot Analysis: 0.01 µg/ml of this antibody detected Brain lipid-binding protein in 10 µg of P1 mouse brain tissue lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions Stable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size 100 µg
Transport Information
Supplemental Information
Specifications

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