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UbcH8 Conjugating Enzyme

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号:14-814

牌:Millipore 密理博

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Replacement Information

重要规格表

Entrez Gene Number Species Uni Prot Number
NM_152653.2 Human Q96LR5
Description
Catalogue Number 14-814
Brand Family Upstate
Trade Name
  • Upstate
Description UbcH8 Conjugating Enzyme, 100 µg
Overview UbcH8 is a class I ubiquitin-conjugating (E2) enzyme highly similar in structure to UbcH7. UbcH8 is a primary target gene of interferon-alpha and gamma, and recent studies have indicated that UbcH8 is the E2 enzyme for the ubiquitin-like protein ISG15. These studies suggest overlap between the ISG15 and ubiquitin conjugation pathways, and have important implications for understanding the regulation and function of ISG15 in the IFN alpha/beta response. Typical enzyme concentration to support conjugation in vitro is 100nM to 1μM depending upon conditions.
References
Product Information
Applications
Application UbcH8 is a class I ubiquitin-conjugating (E2) enzyme highly similar in structure to UbcH7. UbcH8 is a primary target gene of interferon-alpha & gamma.
Biological Information
Source expressed in E. coli
Entrez Gene Number
Gene Symbol
  • UBE2E2
  • FLJ25157
  • UbcH8
  • UBCH8
Purification Method Purified using Ni2+ chelation chromatography with Ni2+ in limiting concentration.
UniProt Number
UniProt Summary FUNCTION: SwissProt: Q96LR5 # Catalyzes the covalent attachment of ubiquitin to other proteins (Probable).
SIZE: 201 amino acids; 22255 Da
SIMILARITY: SwissProt: Q96LR5 ## Belongs to the ubiquitin-conjugating enzyme family.
Molecular Weight 18 kDa
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions For long term storage store at -80°C.
Packaging Information
Material Size 100 µg
Transport Information
Supplemental Information
Specifications

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