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Rb X UbcH6

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促销价：: ¥0.00

货号：AB3858

品牌：Millipore 密理博

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北京朝阳

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EA (预计3-5工作日到货)

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重要规格表

Species Reactivity	Key Applications	Host	Format	Antibody Type
H	IP, WB	Rb	Affinity Purified	Polyclonal Antibody

Description
Catalogue Number	AB3858
Brand Family	Chemicon®
Trade Name	Chemicon
Description	Anti-UbcH6 Antibody
Alternate Names	Ubiquitin-conjugating Enzyme E2 E1 Ubiquitin-protein Ligase E1 Ubiquitin Carrier Protein E1
Background Information	UbcH6 is a closely related member of the UbcH5 and UBC4 subfamily in amino-acid identity but cannot substitute for UbcH5 in many HECT-domain mediated events. UbcH6 is implicated in ER degradation of aberrant proteins.

References

Product Information
Format	Affinity Purified
Presentation	Protein A purified immunoglobulin. Liquid in PBS, pH 7.4.

Applications
Application	Anti-UbcH6 Antibody is an antibody against UbcH6 for use in IP & WB.
Key Applications	Immunoprecipitation Western Blotting
Application Notes	Western blot: 1:100-1:1000 Immunoprecipitation Optimal working dilutions must be determined by end user.

Biological Information
Immunogen	Full length, highly purified, UbcH6 protein.
Host	Rabbit
Specificity	Recognizes UbcH6.
Species Reactivity	Human
Antibody Type	Polyclonal Antibody
Entrez Gene Number	NM_003341.3 NM_182666.1
Entrez Gene Summary	The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Gene Symbol	UBE2E1 UbcH6 UBCH6 EC 6.3.2.19
UniProt Number	P51965
UniProt Summary	FUNCTION: SwissProt: P51965 # Catalyzes the covalent attachment of ubiquitin to other proteins. Mediates the selective degradation of short-lived and abnormal proteins. SIZE: 193 amino acids; 21404 Da SUBUNIT: Interacts with RNF14. SIMILARITY: SwissProt: P51965 ## Belongs to the ubiquitin-conjugating enzyme family.

Physicochemical Information

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements
Usage Statement	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage and Shipping Information
Storage Conditions	Maintain at -70°C in undiluted aliquots for up to 12 months after date of receipt. Avoid repeated freeze/thaw cycles. May be stored at 2-8°C for up to 1 month.

Packaging Information
Material Size	200 µL

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Supplemental Information

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