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Qiagen 凯杰 Biosharp Omega

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Anti-Nectin-2/PVRL2 (CD112), clone R2.525 (mouse monoclonal)

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货号：MABT62

品牌：Millipore 密理博

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Replacement Information

特卖

100% Performance Guaranteed

重要规格表

Species Reactivity Key Applications Host Format Antibody Type
H FC, ELISA M PE Monoclonal Antibody
Description
Catalogue Number MABF344
Replaces MABT462
Description Anti-IL-9 (human) Antibody, PE, clone MH9A4
Alternate Names
  • Interleukin-9
  • IL-9
  • Cytokine P40
  • T-cell growth factor P40
Background Information IL-9 is a cytokine that acts as a regulator of a variety of hematopoietic cells. IL-9 is a potent, T cell-derived, T cell growth factor which can also enhance mast cell activity and IL-3- or IL-4- dependent proliferation of bone marrow derived mast cells. IL-9 promotes erythroid colony formation and has also been reported to protect human T cells from apoptosis induced by IL-2 withdrawal. IL-9 is upregulated in human eosinophils by TNF-alpha and IL1-beta, and has been reported to downregulate the oxidative burst in activated human alveolar macrophages and induce TGF-beta production. Recent studies have shown that Th-9 helper cell lineage is characterized by the production of IL-9. The gene encoding IL-9 has been identified as a candidate gene for asthma. Genetic studies on a mouse model of asthma demonstrated that this cytokine is a determining factor in the pathogenesis of bronchial hyperresponsiveness.
References
Product Information
Format PE
Presentation Purified mouse conjugate antibody in buffer containing PBS (pH 7.2) with up to 0.1% sodium azide and 0.2% (w/v) BSA.
Applications
Application Detect IL-9 using this mouse monoclonal antibody, Anti-IL-9 (human) Antibody, PE, clone MH9A4 validated for use in Flow Cytometry & ELISA.
Key Applications
  • Flow Cytometry
  • ELISA
Application Notes ELISA Analysis: A representative lot detected human IL-9 in ELISA. (Chang HC, et al. 2010)
Biological Information
Immunogen Baculovirus-expressed, recombinant human IL-9
Clone MH9A4
Concentration Please refer to the Certificate of Analysis for the lot-specific concentration.
Host Mouse
Isotype IgG2bκ
Species Reactivity
  • Human
Antibody Type Monoclonal Antibody
Gene Symbol
  • IL9
Purification Method Affinity
UniProt Number
Molecular Weight 16 kDa calculated
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality Assurance The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.

Flow Cytometry Analysis: 5 μL of this antibody detected IL-9 in one million enriched human CD4+ T cells.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions The antibody solution should be stored undiluted at 2-8°C and protected from prolonged exposure to light. Do not freeze.
Packaging Information
Material Size 100 tests
Transport Information
Supplemental Information
Specifications

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