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Rt X E-Selectin Monoclonal Antibody

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货号：MAB2153

品牌：Millipore 密理博

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重要规格表

Species Reactivity Key Applications Host Format Antibody Type
H, M ELISA, FC, IP, WB, FUNC R Purified Monoclonal Antibody
Description
Catalogue Number MAB2153
Brand Family Chemicon®
Trade Name
  • Chemicon
Description Anti-E-Selectin Antibody, lectin domain, clone UZ4
Alternate Names
  • CD62E
  • ELAM-1
References
Product Information
Format Purified
Applications
Application Anti-E-Selectin Antibody, lectin domain, clone UZ4 is an antibody against E-Selectin for use in ELISA, FC, IP & WB.
Key Applications
  • ELISA
  • Flow Cytometry
  • Immunoprecipitation
  • Western Blotting
  • Affects Function
Applications Not Recommended
  • Immunohistochemistry
Biological Information
Immunogen IgM
Epitope lectin domain
Clone UZ4
Host Rat
Species Reactivity
  • Human
  • Mouse
Antibody Type Monoclonal Antibody
Entrez Gene Number
Entrez Gene Summary The endothelial leukocyte adhesion molecule-1 is expressed by cytokine-stimulated endothelial cells. It is thought to be responsible for the accumulation of blood leukocytes at sites of inflammation by mediating the adhesion of cells to the vascular lining. It exhibits structural features such as the presence of lectin- and EGF-like domains followed by short consensus repeat (SCR) domains that contain 6 conserved cysteine residues. These proteins are part of the selectin family of cell adhesion molecules. This gene is present in single copy in the human genome and contains 14 exons spanning about 13 kb of DNA. Adhesion molecules participate in the interaction between leukocytes and the endothelium and appear to be involved in the pathogenesis of atherosclerosis.
Gene Symbol
  • SELE
  • LECAM2
  • ESEL
  • ELAM
  • ELAM-1
  • CD62E
  • ELAM1
UniProt Number
UniProt Summary FUNCTION: SwissProt: P16581 # Expressed on cytokine induced endothelial cells and mediates their binding to leukocytes. The ligand recognized by ELAM-1 is sialyl-lewis X (alpha(1->3)fucosylated derivatives of polylactosamine that are found at the nonreducing termini of glycolipids).
SIZE: 610 amino acids; 66655 Da
SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.
SIMILARITY: SwissProt: P16581 ## Belongs to the selectin/LECAM family. & Contains 1 C-type lectin domain. & Contains 1 EGF-like domain. & Contains 6 Sushi (CCP/SCR) domains.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Packaging Information
Material Size 100 µg
Transport Information
Supplemental Information
Specifications

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