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Anti-Superoxide Dismutase 2 (SOD2) (rabbit polyclonal)

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货号：AB10346

品牌：Millipore 密理博

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重要规格表

Species Reactivity Key Applications Host Format Antibody Type
H, R, M WB Rb Serum Polyclonal Antibody
Description
Catalogue Number AB10346
Brand Family Chemicon®
Trade Name
  • Chemicon
Description Anti-SOD2 Antibody
Alternate Names
  • Superoxide Dismutase 2 (SOD2)
Background Information This gene is a member of the iron/manganese superoxide dismutase family. It encodes a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
References
Product Information
Format Serum
Presentation Raw rabbit serum with 0.05% sodium azide.
Applications
Application This Anti-SOD2 Antibody is validated for use in WB for the detection of SOD2.
Key Applications
  • Western Blotting
Application Notes Western Blot: 1:5000
Biological Information
Immunogen Recombinant human SOD2
Epitope AA G93 – Y217
Host Rabbit
Species Reactivity
  • Human
  • Rat
  • Mouse
Antibody Type Polyclonal Antibody
Entrez Gene Number
Entrez Gene Summary This gene is a member of the iron/manganese superoxide dismutase family. It encodes a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Gene Symbol
  • EC 1.15.1.1
  • IPO-B
  • MNSOD
  • Mn-SOD
  • MnSOD
UniProt Number
UniProt Summary FUNCTION: SwissProt: P04179#Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
SIZE: 222 amino acids; 24722 Da
SUBCELLULAR LOCATION: Mitochondrion matrix.
SIMILARITY: SwissProt: P04179# Belongs to the iron/manganese superoxide dismutase family.
Molecular Weight 28 kDa
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality Assurance Routinely evaluated by immunoblot.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions Maintain at -20°C for up to 12 months from date of receipt.
Packaging Information
Material Size 50 µL
Transport Information
Supplemental Information
Specifications

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