Anti-p27 (Kip1), clone Y236 (rabbit monoclonal) - 炼石商城

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Anti-p27 (Kip1), clone Y236 (rabbit monoclonal)

市场价：: 0.00

促销价：: ¥0.00

货号：04-240

品牌：Millipore 密理博

配送至：

北京朝阳

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数量：

EA (预计3-5工作日到货)

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重要规格表

Species Reactivity	Key Applications	Host	Format	Antibody Type
H	WB	M	Ascites	Monoclonal Antibody

Description
Catalogue Number	MABE634
Replaces	04-240
Description	Anti-CDKN1B , clone 3D8 Antibody
Alternate Names	Cyclin-dependent kinase inhibitor 1B Cyclin-dependent kinase inhibitor p27 p27Kip1 CDKN1B
Background Information	Cyclin-dependent kinase inhibitor 1B (CDKN1B) is a cell cycle regulatory mitotic inhibitor of cdk activity. CDKN1B is a candidate tumor suppressor gene, and has been proposed to function as a possible mediator of TGF beta induced G1 arrest. CDKN1B is up regulated in response to antimitogenic stimuli. The increased protein expression of p27 results in cellular arrest by binding to cyclin/Cdk complexes such as cyclin D1/Cdk4. Decreased levels of p27Kip1, mainly due to proteosomal degradation, are found in various epithelial tumors originating from lung, breast, colon, ovary, esophagus, thyroid and prostate.Tissue specificity: Expressed in all tissues tested. Highest levels in skeletal muscle, lowest in liver and kidney.

References

Product Information
Format	Ascites
Presentation	Mouse monoclonal IgG2ascitic fluid containing 0.03% sodium azide.

Applications
Application	Anti-CDKN1B Antibody, clone 3D8 is an antibody against CDKN1B for use in Western Blotting.
Key Applications	Western Blotting

Biological Information
Immunogen	Purified recombinant fragment of human CDKN1B expressed in E. Coli.
Clone	3D8
Concentration	Please refer to lot specific datasheet.
Host	Mouse
Isotype	IgG2
Species Reactivity	Human
Antibody Type	Monoclonal Antibody
Gene Symbol	CDKN1B KIP1
Purification Method	Unpurified
UniProt Number	P46527
Molecular Weight	~55 kDa observed. Uncharacterized bands may be observed in some lysate(s).

Physicochemical Information

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements
Quality Assurance	Evaluated by Western Blotting in hIgGFc transfected HEK293 cell lysate . Western Blotting Analysis (WB): A 1:500-2,000 dilution of this antibody detected CDKN1B in hIgGFc transfected HEK293 cell lysate.
Usage Statement	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage and Shipping Information
Storage Conditions	Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

Packaging Information
Material Size	100 µL

Transport Information

Supplemental Information

Specifications

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