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Anti-Interleukin-22 (IL-22), clone 2D5 (mouse monoclonal)

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货号：MABF49

品牌：Millipore 密理博

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重要规格表

Species Reactivity Key Applications Host Format Antibody Type
H WB M Purified Monoclonal Antibody
Description
Catalogue Number MABF49
Description Anti-Interleukin-22 (IL-22) Antibody, clone 2D5
Alternate Names
  • interleukin 22
  • Cytokine Zcyto18
  • IL-10-related T-cell-derived-inducible factor
  • interleukin 21
  • interleukin-22
  • IL-10-related T-cell-derived inducible factor
Background Information Interleukin-22 (IL-22) is a human cytokine that is structurally related to IL-10 and secreted by activated Th1 cells. IL-22 is thought to directly activate innate, nonspecific immunity in tissues. IL-22 has also been shown to be pivotal in skin inflammation and wound healing. IL-22 is also shown to be increased during active Crohn’s disease. IL-22 may be a great clinical target for chronic inflammatory diseases.
References
Product Information
Format Purified
Control
  • Human IL-22 recombinant protein
Presentation Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Applications
Application Anti-Interleukin-22 (IL-22) Antibody, clone 2D5 detects level of Interleukin-22 (IL-22) & has been published & validated for use in WB.
Key Applications
  • Western Blotting
Application Notes ELISA Analysis: A previous lot was sued by an independent laboratory in ELISA ( Dr. Gerard Zurawski, Baylor Institute for Immunology Research, Dallas, TX.).
Biological Information
Immunogen Recombinant protein corresponding to human IL-22.
Clone AB55.67.15E11.2D5
Concentration Please refer to the Certificate of Analysis for the lot-specific concentration.
Host Mouse
Isotype IgG1κ
Species Reactivity
  • Human
Antibody Type Monoclonal Antibody
Entrez Gene Number
Gene Symbol
  • ILTIF
  • IL-22
  • IL21
  • IL-TIF
  • TIFIL-23
  • IL-D110
  • TIFa
  • zcyto18
  • IL-21
  • ZCYTO18
Purification Method Protein G Purified
UniProt Number
UniProt Summary FUNCTION: Cytokine that contributes to the inflammatory response in vivo.

SUBCELLULAR LOCATION: Secreted.

SEQUENCE SIMILARITIES: Belongs to the IL-10 family.
Molecular Weight ~17 kDa observed
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality Assurance Evaluated by Western Blot in lysate from cells expressing human IL-22 recombinant protein.

Western Blot Analysis: 0.5 µg/mL of this antibody detected 10 µg of human IL-22 recombinant protein.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions Stable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size 100 µg
Transport Information
Supplemental Information
Specifications

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