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Qiagen 凯杰 Biosharp Omega

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Anti-14-3-3s, clone CS112-2A8

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号:05-632

牌:Millipore 密理博

账期 货到付款

EA (预计3-5工作日到货)

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Replacement Information

重要规格表

Species Reactivity Key Applications Host Format Antibody Type
H, M, R IP, WB M Purified Monoclonal Antibody
Description
Catalogue Number 05-632
Brand Family Upstate
Trade Name
  • Upstate
Description Anti-14-3-3σ Antibody, clone CS112-2A8
Alternate Names
  • Stratifin
References
Product Information
Format Purified
Control
  • Positive Control Included: EGF stim A431 Cell Lysate (12-302). Other controls: Lung tissue
Presentation Protein G Purified immunoglobulin in 30% glycerol, 0.07M Tris-glycine, pH 7.4, 0.105 M NaCl, 0.035% sodium azide as a preservative.
Applications
Application Detect 14-3-3σ using this Anti-14-3-3σ Antibody, clone CS112-2A8 validated for use in IP & WB.
Key Applications
  • Immunoprecipitation
  • Western Blotting
Biological Information
Immunogen GST fusion protein corresponding to full-length human 14-3-3 sigma
Clone CS112-2A8
Host Mouse
Specificity Recognizes 14-3-3σ, does not cross-react with other 14-3-3 isoforms.
Isotype IgG1κ
Species Reactivity
  • Human
  • Mouse
  • Rat
Antibody Type Monoclonal Antibody
Entrez Gene Number
Gene Symbol
  • SFN
  • YWHAS
  • HME1
  • stratifin
  • Stratifin
Purification Method Protein G Purified
UniProt Number
UniProt Summary FUNCTION: SwissProt: P31947 # p53-regulated inhibitor of G2/M progression.
SIZE: 248 amino acids; 27774 Da
SUBUNIT: Homodimer. Interacts with KRT17 (By similarity). Found in a complex with XPO7, EIF4A1, ARHGAP1, VPS26A, VPS29, VPS35 and SFN.
SUBCELLULAR LOCATION: Cytoplasm. Nucleus (By similarity). Secreted. Note=May be secreted by a non-classical secretory pathway.
TISSUE SPECIFICITY: Present mainly in tissues enriched in stratified squamous keratinising epithelium.
SIMILARITY: SwissProt: P31947 ## Belongs to the 14-3-3 family.
Molecular Weight 30 kDa
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality Assurance routinely evaluated by immunoblot on RIPA lysates of EGF-stimulated A431 cells
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions Maintain for 2 years at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Packaging Information
Material Size 200 µg
Transport Information
Supplemental Information
Specifications

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