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Imiquimod盐酸盐是TLR7激动剂，可作为免疫调节剂。
| Description | Imiquimod hydrochloride is an immune response modifier that acts as a toll-like receptor 7agonist. | ||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IC50 & Target | Toll-like receptor 7 | ||||||||||||||||
| In Vivo | In animal models, imiquimod stimulates the innate immune response by increasing NK cell activity, activating macrophages to secrete cytokines and nitric oxide, and inducing proliferation and differentiation of B lymphocytes. Imiquimod stimulates the innate immune response through induction, synthesis, and release of cytokines, including interferon-a (IFN-α), interleukin (IL)-6, and tumour necrosis factor (TNF)-α[1]. | ||||||||||||||||
| Solvent & Solubility | In Vitro: 10 mM in DMSO Preparing Stock Solutions
* Please refer to the solubility information to select the appropriate solvent. | ||||||||||||||||
| References |
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