Biotin-VAD-FMK是可渗透细胞的,不可逆的,由生物素标记的胱天蛋白酶抑制剂,用于鉴定细胞裂解物中的半胱天冬酶活性。
Description | Biotin-VAD-FMK is a cell permeable, irreversible biotin-labeled caspase inhibitor, used to identify active caspases in cell lysates. | ||||||||||||||||
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IC50 & Target[1] |
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In Vitro | Biotin-VAD-FMK is a synthetic peptide designed as a methyl ester to facilitate cell permeability. | ||||||||||||||||
In Vivo | To examine whether caspase-2 is activated in the absence of proteolytic cleavage, an in vivo affinity labeling approach is used, using the biotinylated caspase inhibitor biotin-VAD-fmk that detects only active caspases[2]. | ||||||||||||||||
Solvent & Solubility | In Vitro: DMSO : ≥ 27.3 mg/mL (40.58 mM) * "≥" means soluble, but saturation unknown. Preparing Stock Solutions
* Please refer to the solubility information to select the appropriate solvent. | ||||||||||||||||
References | |
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