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PUMA BH3 是一种 p53 正向凋亡调控因子 (PUMA) BH3结构域多肽，作为 Bak 的直接激活剂，Kd 值为 26 nM。
| Description | PUMA BH3 is a p53 upregulated modulator of apoptosis (PUMA) BH3 domain peptide, acts as a direct activator of Bak, with a Kd of 26 nM. | ||||||||||||||||
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| IC50 & Target[1] |
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| In Vitro | PUMA BH3 is a p53 upregulated modulator of apoptosis (PUMA) BH3 domain peptide, acts as a direct activator of Bak, with a Kd of 26 nM. PUMA BH3 binds Bak in the canonical BH3-binding groove, and activates Bak[1]. | ||||||||||||||||
| Solvent & Solubility | In Vitro: 10 mM in H2O Preparing Stock Solutions
* Please refer to the solubility information to select the appropriate solvent. | ||||||||||||||||
| References |
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