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Qiagen 凯杰 Biosharp Omega

首页酶、辅酶及抑制剂MCE>

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Tobramycin 纯度:>98.0% 5g

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号:HY-B0441

牌:MCE

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工作时间

周一至周五:9:00-18:00

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0771-3293894

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Tobramycin是氨基糖苷类广谱抗生素,由黑暗链霉菌产生。

Description

Tobramycin is an aminoglycoside, broad-spectrum antibiotic produced by Streptomyces tenebrarius. Target: Antibacterial Tobramycin is an aminoglycoside antibiotic derived from Streptomyces tenebrarius and used to treat various types of bacterial infections, particularly Gram-negative infections. It is especially effective against species of Pseudomonas [1]. Tobramycin works by binding to a site on the bacterial 30S and 50S ribosome, preventing formation of the 70S complex. As a result, mRNA cannot be translated into protein and cell death ensues. Tobramycin is preferred over gentamicin for Pseudomonas aeruginosa pneumonia due to better lung penetration. From Wikipedia [2].

Solvent & Solubility
In Vitro:  

H2O : ≥ 200 mg/mL (427.80 mM)

* "≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.1390 mL 10.6950 mL 21.3899 mL
5 mM 0.4278 mL 2.1390 mL 4.2780 mL
10 mM 0.2139 mL 1.0695 mL 2.1390 mL
* Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

467.51

Formula

C₁₈H₃₇N₅O₉

CAS No.

32986-56-4

SMILES

O[C@@H]([C@@H]1O[C@@]([C@@H](C[C@@H]2O)N)([H])O[C@@H]2CN)[C@H]([C@@H](C[C@@H]1N)N)O[C@@]([C@@H]([C@@H](N)[C@@H]3O)O)([H])O[C@@H]3CO

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

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