Solithromycin是一种新颖的氟代酮内酯类抗菌药, 具有抗微生物效力。
Description | Solithromycin is a novel fluoroketolide with improved antimicrobial effectiveness. Target: Antibacterial Solithromycin binds to the large 50S subunit of the ribosome and inhibits protein biosynthesis. The mean 50% inhibitory concentrations (IC50s) for Solithromycin inhibition of cell viability, protein synthesis, and growth rate were 7.5, 40, and 125 ng/ml for Streptococcus pneumoniae,Staphylococcus aureus, and Haemophilus influenzae, respectively. | ||||||||||||||||
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Solvent & Solubility | In Vitro: DMSO : ≥ 32 mg/mL (37.87 mM) * "≥" means soluble, but saturation unknown. Preparing Stock Solutions
* Please refer to the solubility information to select the appropriate solvent. | ||||||||||||||||
References |
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