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Qiagen 凯杰 Biosharp Omega

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Recombinant Human IL-7 500ug

价:
18300.00
价:
¥14640.00

号:P00023-500ug

牌:Solarbio索莱宝

账期 货到付款

EA (预计5-10工作日到货)

工作时间

周一至周五:9:00-18:00

咨询电话

0771-3293894

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客服 郭恒 蔡玉坤 曾宪飞 技术咨询

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Known as Interleukin-7; IL-7; IL7
Derived from E.coli
Purity Greater than 95% as determined by reducing SDS-PAGE.Less than 0.1 ng/?g (1 IEU/?g).
Formulation Lyophilized from a 0.2 μm filtered solution of 20mM PB, 250mM NaCl, pH 7.2.
Shipping The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.
Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 7 months
Reconstitution Always centrifuge tubes before opening. Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in 5X PBS.Please aliquot the reconstituted solution to minimize freeze-t cycles.
Amino Acid Sequence MDCDIEGKDGKQYESVLMVSIDQLLDSMKEIGSNCLNNEFNFFKRHICDANKEGMFLFRAARKLRQFLKMNSTGDFDLHLLKV SEGTTILLNCTGQVKGRKPAALGEAQPTKSLEENKSLKEQKKLNDLCFLKRLLQEIKTCWNKILMGTKEH
Background Human Interleukin 7 (IL-7) is a potent lymphoid cell growth factor stimulating the proliferation of lymphoid progenitors. IL7 can associate with the hepatocyte growth factor (HGF) to form a hybrid cytokine that functions as a pre-pro-B cell growth-stimulating factor. Human IL7 cDNA encodes a 177 amino acid precursor protein containing a 25 amino acid signal peptide and a 152 amino acid mature protein. Human and mouse IL7 share 65% sequence identity in the mature region and both exhibit cross-species activity. IL-7 signals via IL-7 receptor (IL7R) activating multiple pathways including JaK/STAT and PI3K/AKT, which regulate lymphocyte survival, glucose uptake, proliferation, and differentiation. IL-7 is also associated with cytoplasmic IL2-R gamma for signal transduction.

Recombinant Human Interleukin-7 is produced by our E.coli expression system and the target gene encoding
Asp26-His177 is expressed.

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