描述

Cell Therapy Systems (CTS™) Recombinant Human Interleukin 6 (IL6) is a bioactive protein intended for use in cell culture applications, including pre-clinical and clinical cell therapy studies. IL6 is a pleotropic cytokine involved in several cellular processes including inflammation, hematopoeisis, and immune response. The lyophilized, E. coli-expressed IL6 CTS™ Recombinant Human is verified for activity through dose-dependent proliferation of mouse B9 cells.

• Qualified—helps reduce your burden in qualifying reagents for regulatory submission in cell therapy applications
• Highly Pure—minimizes interference from other proteins or contaminants
• Active—get more results with less protein

Simplified Transition into Clinical Research
GIBCO® Cell Therapy Systems (CTS™) products are of high quality and supplied with harmonized documentation such as Certificates of Analysis, Certificates of Origin, and access to authorization letters for our Drug Master Files, as appropriate. The GIBCO® CTS™ product line enables you to reduce your burden in qualifying reagents during your transition from research applications to clinical applications.

High Purity
To help verify that GIBCO® CTS™ Recombinant growth factors are of the highest quality, each protein is analyzed for purity, along with structural homogeneity, to help ensure a biologically active protein. The purity of each GIBCO® CTS™ recombinant growth factor is verified by SDS-PAGE to be over 95% pure and to have endotoxin levels below 0.1 ng/μg.

High Biological Activity
All GIBCO® CTS™ Recombinant growth factors are verified for activity. Each lot has its own ED50 determined using an activity assay based on a specific function of the growth factor. The activity of our IL6 CTS™ Recombinant Human growth factor is determined by the dose-dependent proliferation of mouse B9 cells to have an ED50 range of 0.008–0.02 ng/mL (specific activity: 1.25 × 10^8–5.0 × 10^7 units/mg). Optimal concentration for individual applications should be determined by a dose response assay.

Related Links
• Learn More About GIBCO® Cell Therapy Systems (CTS™) Products
• Cell Therapy Systems Technical Support Web Page
• Our Full Collection of GIBCO® CTS™ Growth Factors
• Our Full Collection of GIBCO® Growth Factors

规格

Research Category:	Bone Research, Clinical Research, Immunology, Inflammation, Stem Cell Research
Activity:	0.008 ng/ml
Bioassay:	Proliferation of B9 cells
Endotoxin Level:	< 0.1 ng/µg
Expression:	E. coli
Gene Aliases:	IL-6 (Interleukin 6)
Molecular Weight:	21.3 kDa
Product Line:	CTS™
Product Size:	100 µg
Protein Family:	Cytokines & Receptors
Protein Form:	Full Length, Ligand, Recombinant
Protein Length or Portion (a.a.):	184 aa
Protein Subtype:	Interleukins
Purification:	Sequential Chromatography
Purity:	95 %
Purity or Quality Grade:	Carrier-Free
Species:	Human
Validated Application:	Cell Culture
Shipping Condition:	Wet Ice

内容及储存