CD300A qPCR Primer Pairs, Mouse 基本信息
Target Details
Product Details
Component:
1 vial of lyophilized qPCR primer mix (1 nmol each primer, sufficient for 200 numbers of 25 μl reactions).
QPCR Primer Description:
Verified forward and reverse primers for analyzing the quantitative expression of gene.
Application & Quality
应用:
SYBR® Green-based quantitative real-time PCR (qPCR).
质控:
The primer mix has been verified to generate satisfactory qPCR data on Roche Applied-science LightCycler® 480 Ⅱ.
储存 & 运输
运输:
Lyophilized qPCR primer mix is shipped at ambiente temperatura
储存:
The lyophilized product is stable for one year from date of receipt when stored at -20℃. The suspended product is stable for six months from date of receipt when stored at -20℃.
***Sino biological qEASY qPCR primer pairs are used for SYBR Green-based real-time RT-PCR, The primers are designed by using SBI's proprietary primer design algorithm. Our primer collection covers the entire human genomes. It can be widely applied in the quantitative analysis of gene expression.***
Features and Advantages
Unique Primer Design
To avoid genomic DNA amplification, at least one primer is designed crosses the junction of exons according to the conserved region of a specific gene with all variants.
Strict Validation Process
Confirmed in positive organizations; screened the primer with high specificity and high sensitivity.
Uniform PCR conditions, Saving time and cost
~100% amplification curve, ensuring the accuracy of the RNA quantitative
CD300A qPCR Primer Pairs, Mouse Alternative Names
B230315M08Rik qPCR Primer Pairs, Mouse;Clm8 qPCR Primer Pairs, Mouse;LMIR1 qPCR Primer Pairs, Mouse;MAIR-I qPCR Primer Pairs, Mouse;MAIR-Ia qPCR Primer Pairs, Mouse;mcpir1 qPCR Primer Pairs, Mouse;MMAC8 qPCR Primer Pairs, Mouse;Pigr4 qPCR Primer Pairs, Mouse
CD300A Background Information
CMRF35-like molecule 8, also known as CD3 antigen-like family member A, CMRF35-H9, Immunoglobulin superfamily member 12, Inhibitory receptor protein 6, NK inhibitory receptor, CD3a and CMRF35H, is a single-pass type I membrane protein which belongs to the CD3 family. The CD3 family of myeloid immunoglobulin receptors includes activating ( CD3b, CD3e ) and inhibitory members ( CD3a, CD3f ), as well as molecules presenting a negative charge within their transmembrane domain ( CD3c, CD3d ). CD3A / IGSF12 is expressed not only by natural killer (NK) cells but also by T-cell subsets, B-cells, dendritic cells, mast cells, granulocytes and monocytes.It contains one Ig-like V-type ( immunoglobulin-like ) domain. CD3A / IGSF12 is an inhibitory receptor which may contribute to the down-regulation of cytolytic activity in natural killer (NK) cells, and to the down-regulation of mast cell degranulation. CD3c is a functional immune receptor able to deliver activating signals upon ligation in RBL-2H3 mast cells. CD3c signaling is partially mediated by a direct association with the immune receptor tyrosine-based activation motif-bearing adaptor FcεRγ. CD3a and CD3c play an important role in the cross-regulation of TNF-alpha and IFN-alpha secretion from plasmacytoid dendritic cells (pDCs).
Full Name
CD300a molecule
References
Bachelet,I. et al., 2005, J. Immunol. 175:7989-7995. Bachelet,I. et al., 2008, J Immunol. 180 (9):6064-9. Ju,X. et al., 2008, Blood. 112 (4):1184-94. Martínez-Barriocanal,A. et al., 2010, J Biol Chem. 285 (53):41781-94. Lankry,D. et al., 2010, J Immunol. 185 (5):2877-86.